Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.53 |
| ▸ | CASP1 | P29466 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | GLA | P06280 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | CASP7 | P55210 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | PPID | Q08752 | 2/20 | 0.53 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.44 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.44 |
| ▸ | BCL2 | P10415 | 2/20 | 0.43 |
| ▸ | DRD1 | P21728 | 1/20 | 0.43 |
| ▸ | BID | P55957 | 1/20 | 0.43 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.43 |
| ▸ | BCL2L2 | Q92843 | 1/20 | 0.43 |
| ▸ | BCL2L10 | Q9HD36 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11085230 | 1.00 | GAA (0.53) | GAACASP1KDM4EALDH1A1GLA | |
| SCHEMBL18211946 | 0.88 | GAA (0.54) | GAACASP1KDM4EALDH1A1GLA | |
| Sumacetamol SCHEMBL5185790 | 0.86 | GAA (0.55) | GAACASP1KDM4EALDH1A1GLA | |
| Sumacetamol SCHEMBL1134071 | 0.86 | GAA (0.55) | GAACASP1KDM4EALDH1A1GLA | |
| SCHEMBL11079312 | 0.83 | MAPT (0.50) | GAACASP1KDM4EALDH1A1GLA | |
| SCHEMBL11079306 | 0.83 | MAPT (0.50) | GAACASP1KDM4EALDH1A1GLA | |
| SCHEMBL8773289 | 0.76 | ALDH1A1 (0.40) | GAACASP1KDM4EALDH1A1GLA | |
| SCHEMBL1133867 | 0.76 | HSD17B10 (0.49) | GAACASP1KDM4EALDH1A1GLA | |
| SCHEMBL13637924 | 0.75 | KMT2A (0.51) | GAACASP1KDM4EALDH1A1GLA | |
| SCHEMBL12229229 | 0.75 | LMNA (0.46) | GAACASP1KDM4EALDH1A1GLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4482495-A | CHEMICAL INTERMEDIATES FOR ANALGESICS | STERLING DRUG INC. (US) | 1984-11-13 | — | — | US | disclosed |
| US-4405800-A | ANALGESICS | STERLING DRUG INC. (US) | 1983-09-20 | — | — | US | disclosed |
| US-4361703-A | ANALGESICS | STERLING DRUG INC. (US) | 1982-11-30 | — | — | US | disclosed |
| US-4181719-A | Analgesic N-acetyl-para-aminophenyl N'-acetylaminothioalkanoates | STERLING DRUG INC. (US) | 1980-01-01 | — | — | US | disclosed |