Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FABP3 | P05413 | 1/20 | 0.43 |
| ▸ | FABP4 | P15090 | 1/20 | 0.43 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.43 |
| ▸ | HNF4A | P41235 | 1/20 | 0.42 |
| ▸ | KDR | P35968 | 3/20 | 0.41 |
| ▸ | PLK4 | O00444 | 2/20 | 0.41 |
| ▸ | NUAK1 | O60285 | 2/20 | 0.41 |
| ▸ | FLT4 | P35916 | 2/20 | 0.41 |
| ▸ | FLT3 | P36888 | 2/20 | 0.41 |
| ▸ | AURKA | O14965 | 1/20 | 0.41 |
| ▸ | CDK4 | P11802 | 1/20 | 0.41 |
| ▸ | CCND1 | P24385 | 1/20 | 0.41 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | SRC | P12931 | 1/20 | 0.40 |
| ▸ | TEK | Q02763 | 1/20 | 0.40 |
| ▸ | LIG1 | P18858 | 1/20 | 0.40 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.39 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6184759 | 0.78 | KMT2A (0.48) | KDRPLK4NUAK1FLT4FLT3 | |
| SCHEMBL133057 | 0.70 | HNF4A (0.69) | FABP3FABP4FABP5HNF4AKDM4E | |
| SCHEMBL26624744 | 0.70 | HNF4A (0.69) | FABP3FABP4FABP5HNF4AKDM4E | |
| Benzene SCHEMBL28480917 | 0.70 | HNF4A (0.69) | FABP3FABP4FABP5HNF4AKDM4E | |
| Biphenyl SCHEMBL6250985 | 0.70 | HNF4A (0.63) | FABP3FABP4FABP5HNF4AKDM4E | |
| Benzene SCHEMBL1403559 | 0.70 | HNF4A (0.69) | FABP3FABP4FABP5HNF4AKDM4E | |
| SCHEMBL11091390 | 0.70 | KDR (0.47) | KDRPLK4NUAK1FLT4FLT3 | |
| SCHEMBL11091670 | 0.70 | PTGS1 (0.57) | KDRPLK4NUAK1FLT4FLT3 | |
| SCHEMBL11089094 | 0.70 | GSK3B (0.45) | KDRPLK4NUAK1FLT4FLT3 | |
| SCHEMBL11083302 | 0.70 | PTGS1 (0.57) | KDRPLK4NUAK1FLT4FLT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4443616-A | Production of 3-pyrrolin-2-ones | THE PURDUE FREDERICK COMPANY (US) | 1984-04-17 | — | — | US | disclosed |