SCHEMBL11085362

SCHEMBL11085362

Cc1ccccc1-c1ccc2cc3ccccc3cc2c1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CTSD P07339 1/20 0.57
BACE1 P56817 1/20 0.57
TRPA1 O75762 1/20 0.53
GSTP1 P09211 1/20 0.50
LCK P06239 1/20 0.50
KDR P35968 1/20 0.50
JAK3 P52333 1/20 0.50
MAPK14 Q16539 1/20 0.50
ESR2 Q92731 2/20 0.48
ESR1 P03372 1/20 0.48
MCL1 Q07820 1/20 0.46
HDAC4 P56524 1/20 0.46
HDAC2 Q92769 1/20 0.46
HDAC8 Q9BY41 1/20 0.46
ABL1 P00519 1/20 0.46
SLC6A2 P23975 1/20 0.45
SLC6A4 P31645 1/20 0.45
SLC6A3 Q01959 1/20 0.45
HTR7 P34969 1/20 0.43
NR3C1 P04150 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3155647 0.94 CTSD (0.59) CTSDBACE1TRPA1GSTP1LCK
SCHEMBL14417256 0.82 ESR2 (0.73) CTSDBACE1TRPA1ESR2ESR1
SCHEMBL29274331 0.82 GSTP1 (0.64) GSTP1ESR2ESR1HDAC4HDAC2
SCHEMBL28841094 0.82 CYP11B2 (0.59) CTSDBACE1TRPA1GSTP1ABL1
SCHEMBL19440078 0.81 CYP11B2 (0.62) CTSDBACE1TRPA1GSTP1ABL1
SCHEMBL28941804 0.80 CYP1A2 (0.57) CTSDBACE1TRPA1LCKKDR
SCHEMBL30177593 0.80 CYP1A2 (0.57) CTSDBACE1TRPA1LCKKDR
SCHEMBL2557207 0.80 GSTP1 (0.52) CTSDBACE1TRPA1GSTP1LCK
SCHEMBL26154428 0.80 CTSD (0.54) CTSDBACE1TRPA1LCKKDR
SCHEMBL5255693 0.79 TRPA1 (0.57) CTSDBACE1TRPA1LCKKDR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4478753-A HALOMETHYLATION, FORMYLATION, DECYANATION, AND DEHYDROGENATION MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) 1984-10-23 US disclosed
EP-0076639-A1 Production of 11,11,12,12-Tetracyano-9,10-anthraquinodimethane and derivatives thereof MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) 1983-04-13 EP disclosed