SCHEMBL11086471

SCHEMBL11086471

O=C1C(c2ccc(O)cc2)N(CO)C(=O)N1CO

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR2 Q92731 5/20 0.36
ESR1 P03372 4/20 0.36
MMP2 P08253 1/20 0.36
CAPN1 P07384 1/20 0.33
ALDH1A1 P00352 4/20 0.33
KDM4E B2RXH2 4/20 0.33
PKM P14618 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
MEN1 O00255 2/20 0.33
KMT2A Q03164 2/20 0.33
CASP1 P29466 2/20 0.32
HTT P42858 2/20 0.32
CASP7 P55210 1/20 0.32
CYP3A4 P08684 2/20 0.32
CYP2C9 P11712 1/20 0.32
MAPT P10636 2/20 0.32
TDP1 Q9NUW8 1/20 0.32
L3MBTL1 Q9Y468 2/20 0.31
USP2 O75604 1/20 0.31
POLB P06746 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11085028 0.68 LMNA (0.50) ESR2ESR1CAPN1ALDH1A1KDM4E
SCHEMBL11360932 0.66 GAA (0.44) ESR2ESR1ALDH1A1KDM4EPKM
SCHEMBL1461449 0.65 L3MBTL1 (0.42) L3MBTL1
SCHEMBL9634672 0.65 L3MBTL1 (0.38) L3MBTL1
Hydroquinone SCHEMBL10550177 0.55 CA3 (0.73) ESR2ESR1ALDH1A1KDM4EPKM
SCHEMBL198235 0.55 L3MBTL1 (0.76) L3MBTL1
SCHEMBL13853142 0.55 L3MBTL1 (0.48) ALDH1A1SMN1; SMN2MAPTL3MBTL1USP2
SCHEMBL11464542 0.53 ADRA2C (0.33) MEN1KMT2AL3MBTL1LMNA
Hydroquinone SCHEMBL10547720 0.53 ALDH1A1 (0.67) ESR2ESR1ALDH1A1KDM4ESMN1; SMN2
SCHEMBL12157332 0.52 ESR2 (0.47) ESR2ESR1ALDH1A1KDM4EMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4440934-A MICROBIOCIDES PACIFIC CHEMICAL IND. CO., LTD. (KR) 1984-04-03 US disclosed