Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP10 | Q53GL7 | 18/20 | 0.61 |
| ▸ | PARP15 | Q460N3 | 7/20 | 0.55 |
| ▸ | PARP4 | Q9UKK3 | 2/20 | 0.55 |
| ▸ | PARP14 | Q460N5 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | PARP16 | Q8N5Y8 | 1/20 | 0.55 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.55 |
| ▸ | PARP2 | Q9UGN5 | 4/20 | 0.54 |
| ▸ | CA1 | P00915 | 1/20 | 0.52 |
| ▸ | CA2 | P00918 | 1/20 | 0.52 |
| ▸ | PARP1 | P09874 | 1/20 | 0.52 |
| ▸ | MAOB | P27338 | 2/20 | 0.51 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8438444 | 0.83 | PRSS1 (0.63) | — | |
| SCHEMBL20273256 | 0.83 | PARP10 (0.59) | PARP10PARP15PARP4PARP14ALDH1A1 | |
| SCHEMBL27316975 | 0.83 | PARP10 (0.59) | PARP10PARP15PARP4PARP14ALDH1A1 | |
| SCHEMBL8011558 | 0.82 | PKM (0.58) | ALDH1A1CA1CA2 | |
| SCHEMBL17099938 | 0.81 | PARP10 (0.58) | PARP10PARP15PARP4PARP14ALDH1A1 | |
| SCHEMBL2170360 | 0.81 | CA12 (0.42) | ALDH1A1KMT2ACA1CA2MAOB | |
| SCHEMBL9353433 | 0.81 | L3MBTL1 (0.63) | ALDH1A1MAOB | |
| SCHEMBL8727410 | 0.78 | MAPT (0.68) | ALDH1A1KMT2ACA1CA2 | |
| SCHEMBL9171182 | 0.78 | MAPT (0.46) | PARP10ALDH1A1MAOB | |
| SCHEMBL28067530 | 0.78 | PARP10 (0.68) | PARP10PARP15PARP4PARP14ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4458071-A | Process for 1-oxa-β-lactams | ELI LILLY AND COMPANY (US) | 1984-07-03 | — | — | US | disclosed |
| EP-0109302-A1 | Process for 1-oxa-beta-lactams | ELI LILLY AND COMPANY (US) | 1984-05-23 | — | — | EP | disclosed |