Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | WDR5 | P61964 | 9/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 4/20 | 0.46 |
| ▸ | NPC1 | O15118 | 7/20 | 0.45 |
| ▸ | RAB9A | P51151 | 7/20 | 0.45 |
| ▸ | HTT | P42858 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | GFER | P55789 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11187453 | 0.92 | ALDH1A1 (0.51) | WDR5ALDH1A1TP53HPGDHSD17B10 | |
| SCHEMBL7916624 | 0.79 | — | — | |
| SCHEMBL11097275 | 0.74 | WDR5 (0.46) | WDR5ALDH1A1TP53HPGDHSD17B10 | |
| SCHEMBL408221 | 0.73 | LMNA (0.56) | WDR5ALDH1A1TP53HPGDHSD17B10 | |
| SCHEMBL11088975 | 0.73 | HPGD (0.57) | WDR5ALDH1A1TP53HPGDHSD17B10 | |
| SCHEMBL11089313 | 0.73 | WDR5 (0.42) | WDR5ALDH1A1TP53HPGDHSD17B10 | |
| SCHEMBL18007543 | 0.72 | — | — | |
| SCHEMBL24879991 | 0.72 | LMNA (0.54) | WDR5ALDH1A1TP53HPGDHSD17B10 | |
| SCHEMBL13424006 | 0.72 | WDR5 (0.47) | WDR5ALDH1A1TP53HPGDHSD17B10 | |
| SCHEMBL25768436 | 0.72 | LMNA (0.54) | WDR5ALDH1A1TP53HPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116256501-A | Use of metabolic markers alone or in combination in diagnosis and treatment of chronic heart failure | 河南中医药大学 | 2023-06-13 | — | — | CN | disclosed |
| US-4482557-A | 3-Substituted-2-oxo-tetrahydro-pyrrol[1,2-a]pyrimidines having digitalis-like activity | CHINOIN GYOGYSZER ES VEGYESZETI TERMEKEK GYARA RT. (HU) | 1984-11-13 | — | — | US | disclosed |
| US-4367229-A | 3-Substituted-tetrahydro-pyrrolo[1,2-a]pyrimidines and pharmaceutical compositions | CHINOIN GYOGYSZER ES VEGYESZETI TERMEKEK GYARA RT. (HU) | 1983-01-04 | — | — | US | disclosed |