Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.52 |
| ▸ | CYP3A5 | P20815 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.49 |
| ▸ | HTR2A | P28223 | 5/20 | 0.48 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.48 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.48 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.48 |
| ▸ | KMO | O15229 | 1/20 | 0.48 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.47 |
| ▸ | CAMK2A | Q9UQM7 | 3/20 | 0.43 |
| ▸ | FABP4 | P15090 | 1/20 | 0.43 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.43 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.40 |
| ▸ | HRH1 | P35367 | 1/20 | 0.40 |
| ▸ | CCR3 | P51677 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11092316 | 0.87 | CYP3A4 (0.50) | CYP3A4CYP2D6CYP3A5CYP2C19HTR2A | |
| SCHEMBL11094079 | 0.84 | CYP3A4 (0.50) | CYP3A4CYP2D6CYP3A5CYP2C19HTR2A | |
| SCHEMBL11093766 | 0.84 | CHRM1 (0.49) | CXCL8SLC6A4SLC6A2SLC6A3CHRM1 | |
| SCHEMBL11089473 | 0.83 | GAA (0.51) | CYP3A4CYP2C19CXCL8CHRM1CAMK2A | |
| SCHEMBL11481740 | 0.82 | CAMK2A (0.55) | CYP2C19CXCL8CHRM1CAMK2AFABP4 | |
| SCHEMBL11092953 | 0.82 | HTR2A (0.49) | CXCL8HTR2ASLC6A4KCNH2CHRM1 | |
| SCHEMBL11095059 | 0.81 | CXCL8 (0.56) | CYP2C19CXCL8CHRM1CAMK2AFABP4 | |
| SCHEMBL11084311 | 0.81 | CXCL8 (0.75) | CXCL8SLC6A4SLC6A2SLC6A3CHRM1 | |
| SCHEMBL22654316 | 0.80 | LMNA (0.57) | CYP2C19CXCL8SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL11089469 | 0.80 | CXCL8 (0.60) | CXCL8CHRM1CAMK2AFABP4FABP5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4472433-A | Phenoxyphenyl acetic acids and their medicinal use | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1984-09-18 | — | — | US | disclosed |
| EP-0008226-B1 | PHENYL-ALKANOIC ACID DERIVATIVES, THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1983-11-02 | — | — | EP | disclosed |
| EP-0008226-A2 | Phenyl-alkanoic acid derivatives, the preparation thereof and pharmaceutical compositions containing them | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1980-02-20 | — | — | EP | disclosed |