Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 2/20 | 0.49 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.49 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | CXCL8 | P10145 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | PLAU | P00749 | 1/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.39 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11091259 | 0.87 | HTR2A (0.47) | HTR2ASLC6A4 | |
| SCHEMBL11096346 | 0.86 | HTR2A (0.46) | HTR2ASLC6A4KCNH2SMN1; SMN2ATM | |
| SCHEMBL11089473 | 0.83 | GAA (0.51) | CAMK2ACXCL8TDP1PLAULMNA | |
| SCHEMBL11481740 | 0.82 | CAMK2A (0.55) | CAMK2ACXCL8SMN1; SMN2TDP1FFAR1 | |
| SCHEMBL11087396 | 0.82 | CYP3A4 (0.52) | HTR2ASLC6A4CAMK2AKCNH2CXCL8 | |
| SCHEMBL11095059 | 0.81 | CXCL8 (0.56) | CAMK2ACXCL8TDP1PLAUPTGS2 | |
| SCHEMBL11092450 | 0.81 | CXCL8 (0.50) | CAMK2ACXCL8TDP1PLAUPTGS2 | |
| SCHEMBL22654316 | 0.80 | LMNA (0.57) | SLC6A4CAMK2ACXCL8FFAR1PTGS2 | |
| SCHEMBL11093766 | 0.78 | CHRM1 (0.49) | SLC6A4CAMK2ACXCL8PLAUPTGS2 | |
| SCHEMBL11089589 | 0.78 | HSD17B10 (0.46) | CAMK2AHSD17B10CXCL8SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4472433-A | Phenoxyphenyl acetic acids and their medicinal use | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1984-09-18 | — | — | US | disclosed |
| EP-0008226-B1 | PHENYL-ALKANOIC ACID DERIVATIVES, THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1983-11-02 | — | — | EP | disclosed |
| EP-0008226-A2 | Phenyl-alkanoic acid derivatives, the preparation thereof and pharmaceutical compositions containing them | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1980-02-20 | — | — | EP | disclosed |