Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.51 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.45 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | CXCL8 | P10145 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.42 |
| ▸ | PLAU | P00749 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | CFD | P00746 | 1/20 | 0.41 |
| ▸ | PLG | P00747 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5659411 | 0.87 | CXCL8 (0.56) | GAARCE1PTPN7TDP1CAMK2A | |
| SCHEMBL11481740 | 0.86 | CAMK2A (0.55) | GAATDP1CAMK2ACXCL8LMNA | |
| SCHEMBL11092953 | 0.83 | HTR2A (0.49) | TDP1CAMK2ACXCL8LMNACHRM1 | |
| SCHEMBL11087396 | 0.83 | CYP3A4 (0.52) | CAMK2ACXCL8CHRM1CYP3A4CYP2C19 | |
| SCHEMBL11095059 | 0.82 | CXCL8 (0.56) | TDP1CAMK2ACXCL8LMNACHRM1 | |
| SCHEMBL11094218 | 0.81 | TDP1 (0.59) | GAATDP1CXCL8MCL1CHRM1 | |
| SCHEMBL22654316 | 0.81 | LMNA (0.57) | CAMK2ACXCL8LMNAMAPTCHRM1 | |
| SCHEMBL11093766 | 0.80 | CHRM1 (0.49) | CAMK2ACXCL8LMNACHRM1PLAU | |
| SCHEMBL5657889 | 0.78 | HSD17B10 (0.55) | CAMK2ACXCL8CHRM1MEN1KMT2A | |
| SCHEMBL11089589 | 0.76 | HSD17B10 (0.46) | CAMK2ACXCL8MEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4472433-A | Phenoxyphenyl acetic acids and their medicinal use | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1984-09-18 | — | — | US | disclosed |