Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SGK1 | O00141 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | KAT6A | Q92794 | 3/20 | 0.36 |
| ▸ | HTR2B | P41595 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.36 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | HRH1 | P35367 | 1/20 | 0.34 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11086919 | 0.82 | CCR4 (0.49) | SGK1ALDH1A1KDM4ELMNASMN1; SMN2 | |
| SCHEMBL29707957 | 0.79 | CNR2 (0.50) | ALDH1A1KDM4ELMNASMN1; SMN2CNR2 | |
| SCHEMBL7912922 | 0.79 | CNR2 (0.50) | ALDH1A1KDM4ELMNASMN1; SMN2CNR2 | |
| SCHEMBL11092954 | 0.78 | SGK1 (0.40) | SGK1ALDH1A1KDM4EKAT6ASLC22A12 | |
| SCHEMBL15461576 | 0.77 | EPAS1 (0.45) | SGK1ALDH1A1KDM4ELMNASMN1; SMN2 | |
| SCHEMBL11088671 | 0.75 | SLC22A12 (0.41) | SGK1ALDH1A1KAT6ASLC22A12 | |
| SCHEMBL16000126 | 0.74 | LMNA (0.54) | ALDH1A1LMNAKAT6AOPRM1OPRK1 | |
| SCHEMBL11085124 | 0.74 | PTGES2 (0.44) | SGK1ALDH1A1KDM4E | |
| SCHEMBL970204 | 0.74 | TRPV4 (0.42) | SGK1ALDH1A1KDM4EKAT6ASLC22A12 | |
| SCHEMBL11089868 | 0.73 | ALDH1A1 (0.56) | SGK1ALDH1A1KDM4ESMN1; SMN2KAT6A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0033984-B1 | NEW SULPHONYL COMPOUNDS, METHOD OF PREPARING THE NEW COMPOUNDS, AS WELL AS APHICIDAL COMPOSITIONS ON THE BASIS OF THE NEW COMPOUNDS | DUPHAR INTERNATIONAL RESEARCH B.V (NL) | 1984-06-06 | — | — | EP | disclosed |
| US-4379157-A | Sulphonyl compounds, method of preparing the new compounds, as well as aphicidal compositions on the basis of the new compounds | DUPHAR INTERNATIONAL RESEARCH B.V. (NL) | 1983-04-05 | — | — | US | disclosed |
| EP-0033984-A1 | New sulphonyl compounds, method of preparing the new compounds, as well as aphicidal compositions on the basis of the new compounds | DUPHAR INTERNATIONAL RESEARCH B.V (NL) | 1981-08-19 | — | — | EP | disclosed |