Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | PGR | P06401 | 1/20 | 0.43 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.43 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | HRH1 | P35367 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1741190 | 0.81 | ALDH1A1 (0.53) | ALDH1A1MAPTSMN1; SMN2KMT2AMEN1 | |
| SCHEMBL5866532 | 0.79 | KMT2A (0.57) | ALDH1A1MAPTSMN1; SMN2KMT2AMEN1 | |
| SCHEMBL70968 | 0.78 | ERCC5 (0.58) | ALDH1A1MAPTSMN1; SMN2KMT2AMEN1 | |
| SCHEMBL1149674 | 0.78 | MMP8 (0.51) | ALDH1A1SMN1; SMN2KMT2AMEN1NPC1 | |
| SCHEMBL9938810 | 0.77 | TDP1 (0.52) | ALDH1A1MAPTSMN1; SMN2KMT2AMEN1 | |
| SCHEMBL9368594 | 0.76 | KMT2A (0.54) | ALDH1A1MAPTSMN1; SMN2KMT2AMEN1 | |
| SCHEMBL9367250 | 0.76 | KMT2A (0.57) | ALDH1A1MAPTSMN1; SMN2KMT2AMEN1 | |
| SCHEMBL28940553 | 0.76 | PGR (0.55) | ALDH1A1MAPTSMN1; SMN2KMT2ANPC1 | |
| SCHEMBL9372943 | 0.75 | KMT2A (0.50) | ALDH1A1MAPTSMN1; SMN2KMT2AMEN1 | |
| SCHEMBL11087897 | 0.74 | KMT2A (0.51) | ALDH1A1MAPTSMN1; SMN2KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4471129-A | ANTIHISTAMINES | LILLY INDUSTRIES LIMITED (GB) | 1984-09-11 | — | — | US | disclosed |
| US-4448787-A | ANTIALLERGENS | LILLY INDUSTRIES LIMITED (GB) | 1984-05-15 | — | — | US | disclosed |
| US-4304728-A | 2,6-DIHYDROXY-2,5-HEXADIENOIC ACID DERIVATIVES, ANTIHISTAMINE INTERMEDIATES | LILLY INDUSTRIES LIMITED (GB) | 1981-12-08 | — | — | US | disclosed |