Sulfuric Acid

Sulfuric Acid

SCHEMBL11088015

CC(=O)NCCNc1ccccc1.O=S(=O)(O)O

nearest known ligand 0.55

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Known targets — ChEMBL curated mechanism

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

The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MTNR1A P48039 5/20 0.55
MTNR1B P49286 5/20 0.55
CA12 O43570 1/20 0.50
CA4 P22748 1/20 0.50
CA7 P43166 1/20 0.50
CA9 Q16790 1/20 0.50
CA14 Q9ULX7 1/20 0.50
EPHX1 P07099 1/20 0.47
L3MBTL1 Q9Y468 1/20 0.46
CYP3A4 P08684 4/20 0.46
CYP1A2 P05177 4/20 0.46
CYP2D6 P10635 4/20 0.46
HSD17B10 Q99714 2/20 0.46
CLK4 Q9HAZ1 2/20 0.46
NAPRT Q6XQN6 1/20 0.46
USP2 O75604 1/20 0.46
CYP2C19 P33261 1/20 0.46
ALDH1A1 P00352 4/20 0.44
SMN1; SMN2 Q16637 2/20 0.44
GLA P06280 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11843114 0.93 MTNR1A (0.61) MTNR1AMTNR1BCA12CA4CA7
Sulfuric Acid SCHEMBL8540368 0.85 KDM4E (0.53) MTNR1AMTNR1BCA12CA4CA7
Sulfuric Acid SCHEMBL11083725 0.83 PKM (0.47) MTNR1AMTNR1BCA12CA4CA7
SCHEMBL19034691 0.82 ALDH1A1 (0.63) MTNR1AMTNR1BEPHX1L3MBTL1CYP3A4
SCHEMBL8538458 0.78 MTNR1A (0.50) MTNR1AMTNR1BCA9HSD17B10USP2
SCHEMBL3565228 0.77 EPHX1 (0.54) MTNR1AMTNR1BEPHX1L3MBTL1CYP3A4
SCHEMBL7011286 0.77 MTNR1A (0.47) MTNR1AMTNR1BCA12CA4CA7
Sulfuric Acid SCHEMBL8070176 0.77 POLB (0.50) CA12CA9L3MBTL1CYP3A4ALDH1A1
SCHEMBL8535693 0.77 KDM4E (0.59) MTNR1AMTNR1BCA12CA4CA7
SCHEMBL171693 0.77 MAPT (0.65) MTNR1AMTNR1BCA12CA4CA7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4473374-A Nitrated coupler compounds useful in direct dyeing and simultaneous oxidation and direct dyeing of keratinic fibers SOCIETE ANONYME DITE: L'OREAL (FR) 1984-09-25 US disclosed
US-4330291-A Nitrated coupler compounds useful in direct dyeing and simultaneous oxidation and direct dyeing of keratinic fibers SOCIETE ANONYME DITE: L'OREAL (FR) 1982-05-18 US disclosed