Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 7/20 | 0.44 |
| ▸ | MMP12 | P39900 | 7/20 | 0.44 |
| ▸ | MMP13 | P45452 | 7/20 | 0.44 |
| ▸ | MMP14 | P50281 | 7/20 | 0.44 |
| ▸ | MMP8 | P22894 | 6/20 | 0.44 |
| ▸ | MMP16 | P51512 | 6/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | MMP9 | P14780 | 6/20 | 0.42 |
| ▸ | MMP1 | P03956 | 5/20 | 0.42 |
| ▸ | MMP3 | P08254 | 5/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21438038 | 0.79 | ALDH1A1 (0.51) | KMT2AMEN1HPGDRAB9AMAPK1 | |
| SCHEMBL12053317 | 0.77 | GPR35 (0.45) | KMT2AMEN1MAPK1ALDH1A1TDP1 | |
| SCHEMBL11092358 | 0.76 | ALDH1A1 (0.49) | KMT2AMEN1RAB9AMAPK1ALDH1A1 | |
| SCHEMBL4296586 | 0.76 | NLRP3 (0.47) | KMT2AMEN1HPGDRAB9AGAA | |
| SCHEMBL11320759 | 0.76 | MEN1 (0.43) | KMT2AMEN1HPGDGAAMAPK1 | |
| SCHEMBL11089795 | 0.76 | ALDH1A1 (0.43) | KMT2AMEN1HPGDRAB9ANPSR1 | |
| SCHEMBL11088189 | 0.75 | SMN1; SMN2 (0.44) | MMP2MMP12KMT2AMMP9MEN1 | |
| SCHEMBL11094031 | 0.74 | KMT2A (0.44) | MMP2MMP12MMP13MMP14MMP8 | |
| SCHEMBL11090150 | 0.74 | HPGD (0.45) | KMT2AMEN1HPGDRAB9ANPSR1 | |
| SCHEMBL3671243 | 0.74 | MAOA (0.45) | MMP2MMP12MMP13MMP14MMP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4472433-A | Phenoxyphenyl acetic acids and their medicinal use | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1984-09-18 | — | — | US | disclosed |
| EP-0008226-A2 | Phenyl-alkanoic acid derivatives, the preparation thereof and pharmaceutical compositions containing them | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1980-02-20 | — | — | EP | disclosed |