Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | GSK3B | P49841 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7300347 | 0.88 | RAB9A (0.41) | MAOAALDH1A1SMN1; SMN2CA2RAB9A | |
| SCHEMBL10803547 | 0.84 | MAOA (0.42) | MAOAALDH1A1SMN1; SMN2CA2RAB9A | |
| SCHEMBL9830266 | 0.79 | RAB9A (0.67) | ALDH1A1SMN1; SMN2RAB9AKMT2ANPC1 | |
| SCHEMBL4760288 | 0.79 | ALDH1A1 (0.53) | ALDH1A1SMN1; SMN2CA2TSHRKMT2A | |
| SCHEMBL10675503 | 0.77 | MAOA (0.48) | MAOAALDH1A1SMN1; SMN2RAB9AGSK3B | |
| SCHEMBL10352937 | 0.77 | MAOA (0.44) | MAOAALDH1A1SMN1; SMN2RAB9AGSK3B | |
| SCHEMBL7301681 | 0.76 | CACNA1S (0.48) | ALDH1A1SMN1; SMN2TSHRKMT2A | |
| SCHEMBL27552536 | 0.76 | KMT2A (0.45) | ALDH1A1SMN1; SMN2CA2TSHRKMT2A | |
| SCHEMBL7289212 | 0.76 | MAOA (0.47) | MAOAALDH1A1SMN1; SMN2RAB9AGSK3B | |
| SCHEMBL11089059 | 0.75 | MAOA (0.43) | MAOAALDH1A1SMN1; SMN2RAB9AGSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0233291-B1 | 2-ARYLBENZOTHIAZINE DERIVATIVES | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1991-03-13 | — | — | EP | claimed |