Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | DHODH | Q02127 | 1/20 | 0.48 |
| ▸ | KDM6B | O15054 | 1/20 | 0.46 |
| ▸ | KDM4A | O75164 | 1/20 | 0.46 |
| ▸ | KDM5C | P41229 | 1/20 | 0.46 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.46 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.46 |
| ▸ | KDM3A | Q9Y4C1 | 1/20 | 0.46 |
| ▸ | MGAM | O43451 | 2/20 | 0.44 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31556386 | 1.00 | KDM4E (0.50) | KDM4EALDH1A1KMT2AMEN1MAPT | |
| SCHEMBL31556394 | 0.87 | IKBKB (0.45) | KDM4EALDH1A1KMT2AMEN1DHODH | |
| SCHEMBL2001891 | 0.79 | ALDH1A1 (0.57) | KDM4EALDH1A1KMT2AMEN1MAPT | |
| Pyridine SCHEMBL2285312 | 0.79 | ALDH1A1 (0.50) | KDM4EALDH1A1KMT2AMEN1MAPT | |
| SCHEMBL28765720 | 0.76 | KDM4E (0.56) | KDM4EALDH1A1KMT2AMEN1MAPT | |
| SCHEMBL6342333 | 0.75 | LMNA (0.50) | KDM4EALDH1A1KMT2AMEN1MAPT | |
| SCHEMBL8329240 | 0.75 | ALDH1A1 (0.56) | KDM4EALDH1A1KMT2AMEN1MAPT | |
| SCHEMBL4602438 | 0.75 | ALDH1A1 (0.53) | KDM4EALDH1A1KMT2AMEN1MAPT | |
| SCHEMBL28962070 | 0.74 | NPC1 (0.53) | KDM4EALDH1A1KMT2AMEN1MAPT | |
| SCHEMBL8915214 | 0.74 | KDM4E (0.50) | KDM4EALDH1A1KMT2AMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4490535-A | 4-(3- and 4-Chlorocyclohex-3-enyl)pyridine intermediates | ETHYL CORPORATION (US) | 1984-12-25 | — | — | US | disclosed |
| US-4405792-A | Substituted pyridines and their preparation | ETHYL CORPORATION (US) | 1983-09-20 | — | — | US | disclosed |