Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 9/20 | 0.56 |
| ▸ | MMP12 | P39900 | 8/20 | 0.56 |
| ▸ | MMP13 | P45452 | 8/20 | 0.56 |
| ▸ | MMP14 | P50281 | 8/20 | 0.56 |
| ▸ | MMP9 | P14780 | 7/20 | 0.56 |
| ▸ | MMP1 | P03956 | 6/20 | 0.56 |
| ▸ | MMP3 | P08254 | 6/20 | 0.56 |
| ▸ | MMP8 | P22894 | 5/20 | 0.56 |
| ▸ | MMP16 | P51512 | 5/20 | 0.56 |
| ▸ | PTGDR2 | Q9Y5Y4 | 7/20 | 0.45 |
| ▸ | ALB | P02768 | 1/20 | 0.44 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11094199 | 0.88 | MMP2 (0.61) | MMP2MMP12MMP13MMP14MMP9 | |
| SCHEMBL11094089 | 0.88 | MMP1 (0.42) | MMP2MMP12MMP13MMP14MMP9 | |
| SCHEMBL13401706 | 0.85 | MMP2 (0.75) | MMP2MMP12MMP13MMP14MMP9 | |
| SCHEMBL11088439 | 0.79 | MMP2 (0.50) | MMP2MMP12MMP13MMP14MMP9 | |
| SCHEMBL17331336 | 0.78 | MEN1 (0.46) | MMP2MMP12MMP13MMP14MMP9 | |
| SCHEMBL4022064 | 0.77 | MMP2 (0.61) | MMP2MMP12MMP13MMP14MMP9 | |
| SCHEMBL27767504 | 0.76 | PTGS2 (0.46) | MMP2MMP12MMP13MMP14MMP9 | |
| SCHEMBL7583347 | 0.73 | AKR1B1 (0.58) | ALB | |
| SCHEMBL16397052 | 0.72 | AKR1B1 (0.57) | ALB | |
| SCHEMBL4461297 | 0.71 | ABCB11 (0.74) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4472433-A | Phenoxyphenyl acetic acids and their medicinal use | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1984-09-18 | — | — | US | disclosed |
| EP-0008226-A2 | Phenyl-alkanoic acid derivatives, the preparation thereof and pharmaceutical compositions containing them | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1980-02-20 | — | — | EP | disclosed |