Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 1/20 | 0.47 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.47 |
| ▸ | PYGL | P06737 | 1/20 | 0.45 |
| ▸ | CTRB1 | P17538 | 4/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | BACE1 | P56817 | 3/20 | 0.43 |
| ▸ | CTSS | P25774 | 1/20 | 0.43 |
| ▸ | CTSK | P43235 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | SLC6A11 | P48066 | 1/20 | 0.41 |
| ▸ | ALPI | P09923 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | XIAP | P98170 | 1/20 | 0.41 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11028602 | 1.00 | MTNR1A (0.47) | MTNR1AMTNR1BPYGLCTRB1LMNA | |
| SCHEMBL11026867 | 0.97 | MTNR1A (0.45) | MTNR1AMTNR1BPYGLCTRB1LMNA | |
| SCHEMBL11025403 | 0.88 | PYGL (0.48) | MTNR1AMTNR1BPYGLCTRB1 | |
| SCHEMBL11030131 | 0.87 | MTNR1A (0.43) | MTNR1AMTNR1BCTRB1LMNABACE1 | |
| SCHEMBL11028920 | 0.86 | PYGL (0.46) | PYGLBACE1NPC1RAB9ASLC6A11 | |
| SCHEMBL7434134 | 0.85 | CTRB1 (0.55) | MTNR1AMTNR1BPYGLCTRB1LMNA | |
| SCHEMBL7442013 | 0.85 | CTRB1 (0.55) | MTNR1AMTNR1BPYGLCTRB1LMNA | |
| SCHEMBL11191376 | 0.81 | ACE (0.56) | CTSSCTSK | |
| SCHEMBL11191380 | 0.81 | ACE (0.56) | CTSSCTSK | |
| SCHEMBL11023875 | 0.80 | CTSC (0.56) | PYGLBACE1NPC1RAB9ASLC6A11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4474764-A | ANALGESICS | ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYU KAI (JP) | 1984-10-02 | — | — | US | disclosed |