Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.33 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.32 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.32 |
| ▸ | MMP9 | P14780 | 4/20 | 0.32 |
| ▸ | MMP13 | P45452 | 4/20 | 0.32 |
| ▸ | ADAM17 | P78536 | 4/20 | 0.32 |
| ▸ | MMP1 | P03956 | 4/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.31 |
| ▸ | HTR1A | P08908 | 1/20 | 0.31 |
| ▸ | MMP2 | P08253 | 1/20 | 0.31 |
| ▸ | MMP3 | P08254 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10474112 | 0.92 | TSHR (0.39) | TSHRHTR2ASPHK1GPR84SLC2A1 | |
| SCHEMBL10474929 | 0.92 | GPR84 (0.36) | HTR2AGPR84SLC2A1MMP9MMP13 | |
| SCHEMBL10472795 | 0.86 | IDO1 (0.35) | HTR2AGPR84MMP9MMP13MMP1 | |
| SCHEMBL20802184 | 0.82 | GPR84 (0.41) | HTR2AGPR84SLC2A1MMP9MMP13 | |
| SCHEMBL9079558 | 0.82 | GPR84 (0.41) | HTR2AGPR84SLC2A1MMP9MMP13 | |
| SCHEMBL21726743 | 0.79 | GPR84 (0.39) | SPHK1GPR84SLC2A1 | |
| SCHEMBL10474311 | 0.76 | USP2 (0.36) | HTR2ASPHK1GPR84PTGS2 | |
| SCHEMBL10474251 | 0.76 | PTGS2 (0.40) | TSHRHTR2AGPR84PTGS2HTR1A | |
| SCHEMBL11089326 | 0.73 | PTGS2 (0.54) | HTR2AGPR84PTGS2 | |
| SCHEMBL10473607 | 0.73 | MMP1 (0.42) | HTR2AMMP1MMP2MMP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4473704-A | ANALGESICS, ANTIEMETICS | PFIZER INC. (US) | 1984-09-25 | — | — | US | disclosed |