Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | AHR | P35869 | 1/20 | 0.38 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.37 |
| ▸ | MMP1 | P03956 | 2/20 | 0.36 |
| ▸ | MMP9 | P14780 | 2/20 | 0.36 |
| ▸ | MMP13 | P45452 | 2/20 | 0.36 |
| ▸ | ADAM17 | P78536 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20802184 | 1.00 | GPR84 (0.41) | GPR84PTGS2HTR2AALDH1A1AHR | |
| SCHEMBL10474112 | 0.89 | TSHR (0.39) | GPR84PTGS2HTR2ASLC2A1 | |
| SCHEMBL10474929 | 0.89 | GPR84 (0.36) | GPR84PTGS2HTR2ASLC2A1MMP1 | |
| SCHEMBL10472613 | 0.88 | MGLL (0.36) | GPR84PTGS2HTR2AALDH1A1AHR | |
| SCHEMBL10474251 | 0.86 | PTGS2 (0.40) | GPR84PTGS2HTR2A | |
| SCHEMBL10474177 | 0.85 | GPR84 (0.40) | GPR84PTGS2HTR2AALDH1A1AHR | |
| SCHEMBL10471893 | 0.85 | GPR84 (0.40) | GPR84PTGS2HTR2AALDH1A1AHR | |
| SCHEMBL15418608 | 0.85 | ALDH1A1 (0.46) | ALDH1A1AHR | |
| SCHEMBL10472667 | 0.84 | PLA2G2A (0.51) | ALDH1A1 | |
| SCHEMBL10472694 | 0.84 | PLA2G2A (0.51) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5498419-A | SIDE EFFECT REDUCTION | PARS HARRY G (US) | 1996-03-12 | — | — | US | disclosed |