Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 5/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | P4HB | P07237 | 2/20 | 0.40 |
| ▸ | SMAD3 | P84022 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 5/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.39 |
| ▸ | TP53 | P04637 | 3/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | USP2 | O75604 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11084093 | 0.87 | HPGD (0.42) | HPGDLMNAPOLBMAPTTP53 | |
| SCHEMBL11091589 | 0.84 | LMNA (0.41) | HPGDLMNAGAAALDH1A1ALOX15 | |
| SCHEMBL11083004 | 0.80 | CYP1A2 (0.55) | HPGDLMNAP4HBSMAD3GAA | |
| SCHEMBL11091535 | 0.79 | P4HB (0.54) | P4HBSMAD3GAAMAPTKDM4E | |
| SCHEMBL15145035 | 0.71 | LMNA (0.51) | HPGDLMNAPOLBP4HBSMAD3 | |
| SCHEMBL8501757 | 0.69 | TDP1 (0.53) | HPGDLMNAGAAMAPTKDM4E | |
| SCHEMBL5458653 | 0.68 | LMNA (0.64) | HPGDLMNAPOLBMAPTALDH1A1 | |
| SCHEMBL7709780 | 0.68 | CYP3A4 (0.72) | P4HBSMAD3CYP3A4ALOX15MEN1 | |
| SCHEMBL28639731 | 0.66 | KDM4E (0.52) | HPGDLMNAMAPTKDM4EALDH1A1 | |
| SCHEMBL21363793 | 0.66 | CYP3A4 (0.41) | POLBMAPTKDM4EALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4482728-A | ANTIFERTILITY AGENTS | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (US) | 1984-11-13 | — | — | US | disclosed |
| US-4357344-A | Polybutylbenzylphenols and benzyl-3,4-methylenedioxybenzenes in insect population control | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (US) | 1982-11-02 | — | — | US | disclosed |
| US-4342777-A | GROWTH INHIBITOR FOR MOSQUITO LARVAE | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (US) | 1982-08-03 | — | — | US | disclosed |