Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 | O43613 | 1/20 | 0.53 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11100992 | 0.95 | ALDH1A1 (0.52) | ALDH1A1MEN1KMT2AMAPTSIGMAR1 | |
| SCHEMBL11098498 | 0.92 | SIGMAR1 (0.54) | ALDH1A1MEN1KMT2AMAPTSIGMAR1 | |
| SCHEMBL11096830 | 0.91 | SMN1; SMN2 (0.54) | ALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL11100998 | 0.90 | ALDH1A1 (0.50) | ALDH1A1MEN1KMT2AMAPTSIGMAR1 | |
| SCHEMBL11096217 | 0.87 | TSHR (0.57) | ALDH1A1MEN1KMT2ATSHRSIGMAR1 | |
| SCHEMBL11097949 | 0.86 | DRD2 (0.51) | CXCR4TSHR | |
| SCHEMBL11270191 | 0.85 | CXCR4 (0.47) | MEN1KMT2ACXCR4MAPTTSHR | |
| SCHEMBL11270864 | 0.84 | CXCR4 (0.46) | ALDH1A1CXCR4TSHRSIGMAR1 | |
| SCHEMBL11093691 | 0.84 | MAPT (0.56) | ALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL11092428 | 0.83 | DRD2 (0.52) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0031219-A1 | Aniline derivatives | BEECHAM GROUP PLC (GB) | 1981-07-01 | — | — | EP | claimed |
| EP-0031219-B1 | ANILINE DERIVATIVES | BEECHAM GROUP PLC (GB) | 1984-03-07 | — | — | EP | disclosed |
| US-4350691-A | ANTIEMETICS | BEECHAM GROUP LIMITED (GB) | 1982-09-21 | — | — | US | disclosed |
| EP-0031219-A1 | Aniline derivatives | BEECHAM GROUP PLC (GB) | 1981-07-01 | — | — | EP | disclosed |