Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | TSHR | P16473 | 4/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7149943 | 0.84 | ALDH1A1 (0.55) | PKMALDH1A1TSHRLMNAHPGD | |
| SCHEMBL5108684 | 0.78 | KDM4E (0.58) | PKMALDH1A1LMNAHPGDHTT | |
| SCHEMBL28482405 | 0.74 | SMN1; SMN2 (0.66) | ALDH1A1TSHRLMNASMN1; SMN2GAA | |
| SCHEMBL10600602 | 0.73 | PKM (0.49) | PKMALDH1A1TSHRLMNAHPGD | |
| SCHEMBL22639722 | 0.71 | SMN1; SMN2 (0.62) | ALDH1A1TSHRLMNAHPGDSMN1; SMN2 | |
| SCHEMBL7147721 | 0.71 | GAA (0.46) | PKMALDH1A1SMN1; SMN2GAAMEN1 | |
| SCHEMBL12143535 | 0.70 | L3MBTL1 (0.46) | ALDH1A1TSHRLMNASMN1; SMN2GAA | |
| SCHEMBL12142140 | 0.69 | ALDH1A1 (0.40) | PKMALDH1A1HPGD | |
| SCHEMBL512553 | 0.68 | NPSR1 (0.58) | PKMALDH1A1GAAMEN1KMT2A | |
| SCHEMBL7146938 | 0.68 | ALDH1A1 (0.41) | PKMALDH1A1LMNASMN1; SMN2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0110435-A1 | Novel ((bis(aryl)methylene)-1-piperidinyl)alkyl-pyrimidinones | JANSSEN PHARMACEUTICA N.V. (BE) | 1984-06-13 | — | — | EP | disclosed |