Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11089906 | 0.84 | PKM (0.55) | ALDH1A1SMN1; SMN2PKMMCL1HPGD | |
| SCHEMBL5108684 | 0.84 | KDM4E (0.58) | ALDH1A1PKMHPGDKDM4ELMNA | |
| SCHEMBL7147721 | 0.76 | GAA (0.46) | ALDH1A1SMN1; SMN2PKMKDM4E | |
| SCHEMBL10600602 | 0.76 | PKM (0.49) | ALDH1A1PKMHPGDTSHRKDM4E | |
| SCHEMBL12143535 | 0.76 | L3MBTL1 (0.46) | ALDH1A1SMN1; SMN2TSHRKDM4ELMNA | |
| SCHEMBL12142140 | 0.74 | ALDH1A1 (0.40) | ALDH1A1PKMHPGDKDM4E | |
| SCHEMBL1895259 | 0.74 | LMNA (0.74) | ALDH1A1SMN1; SMN2HPGDTSHRLMNA | |
| SCHEMBL512553 | 0.73 | NPSR1 (0.58) | ALDH1A1PKMKDM4E | |
| SCHEMBL7146938 | 0.73 | ALDH1A1 (0.41) | ALDH1A1SMN1; SMN2PKMKDM4ELMNA | |
| SCHEMBL8515731 | 0.72 | KDM4E (0.60) | ALDH1A1PKMMCL1HPGDTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2241567-A1 | BICYCLOAMINE DERIVATIVE | Eisai R&D Management Co., Ltd. (JP) | 2010-10-20 | — | — | EP | disclosed |
| EP-0808313-B1 | ANTIPSYCHOTIC 4-(1H-INDOLYL-1-YL)-1-SUBSTITUTED PIPERIDINE DERIVATIVES | JANSSEN PHARMACEUTICA NV (BE) | 2003-08-13 | — | — | EP | disclosed |
| US-5919788-A | PSYCHOLOGICAL DISORDERS | JANSSEN PHARMACEUTICA, N.V. (BE) | 1999-07-06 | — | — | US | disclosed |
| EP-0808313-A1 | ANTIPSYCHOTIC 4-(1H-INDOLYL-1-YL)-1-SUBSTITUTED PIPERIDINE DERIVATIVES | JANSSEN PHARMACEUTICA N.V. (BE) | 1997-11-26 | — | — | EP | disclosed |
| WO-1996023784-A1 | ANTIPSYCHOTIC 4-(1H-INDOLYL-1-YL)-1-SUBSTITUTED PIPERIDINE DERIVATIVES | JANSSEN PHARMACEUTICA N.V. (BE) | 1996-08-08 | — | — | WO | disclosed |