Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | PKM | P14618 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 7/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 6/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.39 |
| ▸ | PDE7A | Q13946 | 3/20 | 0.39 |
| ▸ | PDE7B | Q9NP56 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrogen Sulfide SCHEMBL9669896 | 0.75 | MAPT (0.49) | MAPTALDH1A1PKMMEN1POLB | |
| SCHEMBL25751893 | 0.73 | PDE7A (0.42) | ALDH1A1LMNASLC6A4SLC6A2SLC6A3 | |
| SCHEMBL10693083 | 0.73 | CA1 (0.63) | MAPTALDH1A1PKMMEN1POLB | |
| SCHEMBL28385019 | 0.72 | G6PD (0.61) | MAPTALDH1A1PKMMEN1KMT2A | |
| SCHEMBL28867147 | 0.70 | G6PD (0.47) | ALDH1A1CYP1A2CYP2C9HPGDCYP2C19 | |
| SCHEMBL914479 | 0.70 | ALDH1A1 (0.64) | MAPTALDH1A1PKMMEN1POLB | |
| SCHEMBL24439551 | 0.70 | SLC6A2 (0.56) | ALDH1A1LMNASLC6A4SLC6A2SLC6A3 | |
| SCHEMBL6937115 | 0.70 | MAPT (0.63) | MAPTALDH1A1PKMMEN1POLB | |
| SCHEMBL24439562 | 0.68 | SLC6A4 (0.44) | ALDH1A1LMNASLC6A4SLC6A2SLC6A3 | |
| SCHEMBL3077036 | 0.68 | ALDH1A1 (0.53) | MAPTALDH1A1PKMMEN1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4482711-A | Process for the preparation of N,N-dimethyl-10-[1-aza-[2,2,2]-bicyclo-3-octyl]-10H-2-phenothiazine sulphonamide | PHARMINDUSTRIE (FR) | 1984-11-13 | — | — | US | disclosed |