Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | EGFR | P00533 | 2/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.47 |
| ▸ | CNR1 | P21554 | 1/20 | 0.46 |
| ▸ | CNR2 | P34972 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.44 |
| ▸ | NMT2 | O60551 | 1/20 | 0.42 |
| ▸ | NMT1 | P30419 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11090303 | 0.81 | KDM4E (0.47) | ALDH1A1MAPTEGFRCNR1CNR2 | |
| SCHEMBL11091059 | 0.81 | EGFR (0.49) | ALDH1A1EGFRKDM4ESMN1; SMN2HTT | |
| SCHEMBL11195099 | 0.75 | EGFR (0.57) | ALDH1A1MAPTEGFREPHX2HPGD | |
| SCHEMBL18614962 | 0.73 | PARP10 (0.52) | MAPTKDM4E | |
| SCHEMBL11117435 | 0.70 | MAPT (0.67) | ALDH1A1MAPTEGFRHPGDSMN1; SMN2 | |
| SCHEMBL7369285 | 0.70 | EGFR (0.48) | ALDH1A1MAPTEGFREPHX2CNR1 | |
| SCHEMBL487963 | 0.69 | ALDH1A1 (0.56) | ALDH1A1MAPTKDM4ELMNAKMT2A | |
| SCHEMBL23235218 | 0.68 | KMT2A (0.78) | ALDH1A1MAPTEGFREPHX2HTT | |
| SCHEMBL1448590 | 0.68 | ALDH1A1 (0.64) | ALDH1A1MAPTKDM4EHPGDHSD17B10 | |
| SCHEMBL10607328 | 0.68 | KMT2A (0.49) | ALDH1A1MAPTCNR1KDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4443603-A | PROTEOLYTIC ENZYME INHIBITORS | KOWA COMPANY LIMITED (JP) | 1984-04-17 | — | — | US | disclosed |
| EP-0067561-A2 | Piperazine derivatives and processes for producing them | KOWA COMPANY, LTD. (JP) | 1982-12-22 | — | — | EP | disclosed |