Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 2/20 | 0.57 |
| ▸ | CD274 | Q9NZQ7 | 2/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | BCL3 | P20749 | 1/20 | 0.51 |
| ▸ | HPGDS | O60760 | 1/20 | 0.50 |
| ▸ | HTR1A | P08908 | 1/20 | 0.50 |
| ▸ | MAOA | P21397 | 1/20 | 0.50 |
| ▸ | MAOB | P27338 | 1/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | MCHR2 | Q969V1 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11090914 | 0.84 | CD274 (0.62) | CD274HPGDALDH1A1EPHX2CYP1A2 | |
| SCHEMBL7230736 | 0.77 | L3MBTL1 (0.63) | EGFRCD274HPGDALDH1A1MEN1 | |
| Hydrochloric Acid SCHEMBL11286050 | 0.76 | HPGDS (0.51) | CD274HPGDALDH1A1MAPTEPHX2 | |
| SCHEMBL7284691 | 0.76 | GLA (0.51) | EGFRMCHR2MCHR1 | |
| SCHEMBL7240543 | 0.76 | GLA (0.61) | EGFRCD274HPGDALDH1A1CYP1A2 | |
| SCHEMBL8549799 | 0.75 | HTR1A (0.53) | EGFRMAPTCYP1A2CYP2D6CYP2C19 | |
| SCHEMBL487964 | 0.75 | CD274 (0.84) | CD274HPGDALDH1A1EPHX2CYP1A2 | |
| SCHEMBL11090305 | 0.75 | ALDH1A1 (0.48) | EGFRHPGDALDH1A1MAPTEPHX2 | |
| SCHEMBL1478626 | 0.74 | SMN1; SMN2 (0.61) | EGFRALDH1A1MAPTPKMCYP2D6 | |
| SCHEMBL12894562 | 0.74 | FAAH (0.61) | ALDH1A1LMNAPKMMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0071433-A1 | Medicine for the treatment of diabetes | KOWA COMPANY, LTD. (JP) | 1983-02-09 | — | — | EP | disclosed |