Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTK2B | Q14289 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.45 |
| ▸ | BCHE | P06276 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | RXRA | P19793 | 1/20 | 0.42 |
| ▸ | RXRB | P28702 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11099024 | 0.85 | MRGPRX4 (0.43) | MEN1KMT2ATP53HTTTDP1 | |
| SCHEMBL8496813 | 0.84 | PTK2B (0.47) | PTK2BMEN1KMT2APKMCXCL8 | |
| SCHEMBL28189795 | 0.82 | MEN1 (0.50) | PTK2BMEN1KMT2APKMCXCL8 | |
| SCHEMBL27645038 | 0.82 | KMT2A (0.46) | PTK2BMEN1KMT2APKMCXCL8 | |
| SCHEMBL28478482 | 0.81 | RXFP1 (0.41) | MEN1KMT2APKMMAPTPOLB | |
| SCHEMBL9799609 | 0.81 | ELANE (0.46) | PTK2BMEN1KMT2APKMCXCL8 | |
| SCHEMBL15442189 | 0.81 | PTK2B (0.45) | PTK2BMEN1KMT2APKMCXCL8 | |
| SCHEMBL30140858 | 0.81 | PTK2B (0.45) | PTK2BMEN1KMT2APKMCXCL8 | |
| SCHEMBL578720 | 0.81 | ELANE (0.46) | PTK2BMEN1KMT2APKMCXCL8 | |
| SCHEMBL8498810 | 0.81 | KMT2A (0.50) | PTK2BMEN1KMT2APKMCXCL8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4461911-A | FROM THIOGLYCOLIC ACID AND AN ARYLDIAZONIUM SALT, COPPER SALT, ACID MEDIUM | BAYER AKTIENGESELLSCHAFT (DE) | 1984-07-24 | — | — | US | disclosed |
| US-RE29523-E | Olefinic polymers stabilized with thioacyl trivalent phosphorus compounds | BORG-WARNER CORPORATION (US) | 1978-01-24 | — | — | US | disclosed |