SCHEMBL28478482

SCHEMBL28478482

O=C(CS)Oc1cccc2cccc(Cl)c12

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RXFP1 Q9HBX9 2/20 0.41
POLB P06746 2/20 0.41
KMT2A Q03164 7/20 0.41
MEN1 O00255 5/20 0.41
ALDH1A1 P00352 2/20 0.41
HSD17B10 Q99714 2/20 0.41
KDM4E B2RXH2 1/20 0.41
TSHR P16473 1/20 0.41
L3MBTL1 Q9Y468 3/20 0.38
LMNA P02545 2/20 0.38
GAA P10253 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
ADRA2A P08913 2/20 0.35
CYP3A4 P08684 1/20 0.35
HTR1A P08908 1/20 0.35
CYP2D6 P10635 1/20 0.35
CYP2C9 P11712 1/20 0.35
ADRA2B P18089 1/20 0.35
ADRA2C P18825 1/20 0.35
MAOA P21397 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11099024 0.81 MRGPRX4 (0.43) KMT2AMEN1ALDH1A1KDM4ETSHR
SCHEMBL11091140 0.81 PTK2B (0.45) POLBKMT2AMEN1LMNASMN1; SMN2
SCHEMBL7761152 0.75 ALDH1A1 (0.56) POLBKMT2AMEN1ALDH1A1HSD17B10
SCHEMBL29728560 0.69 KMT2A (0.50) POLBKMT2AMEN1ALDH1A1HSD17B10
SCHEMBL11601543 0.68 LMNA (0.49) KMT2AALDH1A1HSD17B10TSHRL3MBTL1
SCHEMBL7828574 0.68 ALDH1A1 (0.44) POLBKMT2AMEN1ALDH1A1KDM4E
SCHEMBL9159636 0.68 TDP1 (0.53) KMT2AMEN1ALDH1A1TSHRL3MBTL1
SCHEMBL8749360 0.67 NQO2 (0.44) KMT2AMEN1ALDH1A1HSD17B10KDM4E
SCHEMBL16236027 0.67 KDM4E (0.40) POLBKMT2AMEN1ALDH1A1HSD17B10
SCHEMBL10521757 0.67 TSHR (0.44) KMT2AMEN1ALDH1A1HSD17B10KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107635676-B Pretreatment method for electroless plating 麦克德米德股份有限公司 2020-09-18 CN claimed
CN-107635676-B Pretreatment method for electroless plating 麦克德米德股份有限公司 2020-09-18 CN disclosed