Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | AHR | P35869 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | CASP6 | P55212 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | CCR2 | P41597 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11166536 | 0.86 | PTGDR2 (0.49) | LMNAMEN1KMT2APOLBTDP1 | |
| SCHEMBL11096838 | 0.85 | LMNA (0.41) | LMNAMEN1KMT2APOLBTDP1 | |
| SCHEMBL11099111 | 0.84 | AR (0.52) | MEN1KMT2APOLBKDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL11093963 | 0.78 | CYP1A2 (0.45) | LMNAMEN1KMT2AKDM4ESMN1; SMN2 | |
| SCHEMBL8954292 | 0.77 | ALDH1A1 (0.49) | LMNAMEN1KMT2ARAB9AKDM4E | |
| SCHEMBL11098540 | 0.76 | TP53 (0.53) | LMNAMEN1KMT2AL3MBTL1KDM4E | |
| SCHEMBL7049490 | 0.76 | DCTPP1 (0.42) | LMNAALDH1A1PLA2G2ACCR2CFTR | |
| SCHEMBL11094843 | 0.75 | PTGDR2 (0.52) | LMNAMEN1KMT2APOLBTDP1 | |
| SCHEMBL11090546 | 0.74 | ALDH1A1 (0.54) | LMNARAB9AKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL11129961 | 0.73 | KDM4E (0.43) | LMNAMEN1KMT2AL3MBTL1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0028834-B1 | IMIDAZOLE-5-ACETIC ACID DERIVATIVES, THEIR PRODUCTION AND USE | Takeda Chemical Industries, Ltd. (JP) | 1984-01-18 | — | — | EP | disclosed |
| US-4355040-A | Hypotensive imidazole-5-acetic acid derivatives | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1982-10-19 | — | — | US | disclosed |
| EP-0028834-A1 | Imidazole-5-acetic acid derivatives, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1981-05-20 | — | — | EP | disclosed |