SCHEMBL11093043

SCHEMBL11093043

O=C1c2cccc(I)c2C(=O)N1Br

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSPA1A P0DMV8 1/20 0.33
PABPC1 P11940 1/20 0.33
TDP2 O95551 1/20 0.33
DPP4 P27487 1/20 0.32
MEN1 O00255 3/20 0.31
KMT2A Q03164 3/20 0.31
USP2 O75604 1/20 0.31
CASP1 P29466 1/20 0.31
BRCA1 P38398 1/20 0.31
CASP7 P55210 1/20 0.31
ADORA2A P29274 1/20 0.31
MGLL Q99685 1/20 0.31
ERCC1 P07992 1/20 0.31
FEN1 P39748 1/20 0.31
ERCC4 Q92889 1/20 0.31
KDM4E B2RXH2 2/20 0.30
ALDH1A1 P00352 1/20 0.30
LMNA P02545 1/20 0.30
CES1 P23141 2/20 0.30
BCHE P06276 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3681059 0.78 CA2 (0.44) HSPA1APABPC1DPP4MEN1KMT2A
SCHEMBL30725967 0.76 MEN1 (0.53) MEN1KMT2AUSP2CASP1BRCA1
SCHEMBL4369262 0.76 MEN1 (0.53) MEN1KMT2AUSP2CASP1BRCA1
SCHEMBL1039244 0.76 DPP4 (0.50) DPP4MEN1KMT2AALDH1A1
Ethylene SCHEMBL7198617 0.74 CA2 (0.42) HSPA1APABPC1MEN1KMT2AKDM4E
SCHEMBL7687360 0.74 ANPEP (0.38) HSPA1APABPC1DPP4MEN1KMT2A
SCHEMBL29385866 0.73 POLB (0.48) TDP2MEN1KMT2AKDM4ELMNA
SCHEMBL1771 0.73 POLB (0.48) TDP2MEN1KMT2AKDM4ELMNA
SCHEMBL19288503 0.72 PARP1 (0.37) TDP2DPP4MEN1KMT2AUSP2
SCHEMBL30572531 0.71 POLB (0.46) TDP2MEN1KMT2AKDM4ELMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4442202-A SILVER HALIDE, REDOX SYSTEM, ORGANOBROMINE COMPOUND, STORAGE STABILITY ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) 1984-04-10 US disclosed
US-4396712-A ORGANIC SILVER SALT OXIDIZER, REDUCING AGENT, SILVER HALIDE OR SILVER HALIDE FORMER, TONER, BINDER, HYDROXYPHENYLBENZOTRIAZOLE ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) 1983-08-02 US disclosed
US-4332889-A IMPROVED SENSITIVITY, STORAGE STABILITY ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) 1982-06-01 US disclosed