Ethylene

Ethylene

SCHEMBL7198617

C=C.O=C1c2cccc(Br)c2C(=O)N1Br

nearest known ligand 0.42

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA2 P00918 2/20 0.42
CA1 P00915 1/20 0.42
CA7 P43166 1/20 0.42
CA9 Q16790 1/20 0.42
CYP1B1 Q16678 2/20 0.36
MEN1 O00255 3/20 0.34
ALDH1A1 P00352 3/20 0.34
KMT2A Q03164 3/20 0.34
POLB P06746 2/20 0.34
MAPT P10636 2/20 0.34
PIM1 P11309 1/20 0.34
CSNK1A1 P48729 1/20 0.34
CDK5 Q00535 1/20 0.34
ROCK1 Q13464 1/20 0.34
DYRK1A Q13627 1/20 0.34
LRRK2 Q5S007 1/20 0.34
CLK4 Q9HAZ1 1/20 0.34
DYRK1B Q9Y463 1/20 0.34
HTT P42858 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3681059 0.96 CA2 (0.44) CA2CA1CA7CA9CYP1B1
Ethylene SCHEMBL19283170 0.77 ALDH1A1 (0.30) ALDH1A1POLBRXFP1
SCHEMBL30725968 0.74 MEN1 (0.53) CA2CA1CA7CA9MEN1
SCHEMBL1039244 0.74 DPP4 (0.50) CA2CA1CA7CA9MEN1
SCHEMBL133067 0.74 MEN1 (0.53) CA2CA1CA7CA9MEN1
SCHEMBL11093043 0.74 HSPA1A (0.33) MEN1ALDH1A1KMT2APABPC1HSPA1A
SCHEMBL6656873 0.74 FEN1 (0.52) CA2CA1CA7CA9CYP1B1
SCHEMBL27697384 0.74 ANPEP (0.36) MEN1KMT2APABPC1HSPA1A
SCHEMBL7687360 0.73 ANPEP (0.38) CA2MEN1KMT2APABPC1HSPA1A
SCHEMBL3683888 0.72 S100A4 (0.31) CYP1B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0848033-B1 Flame-retardant resin composition, and insulated wire, shielded wire and insulating tube comprising the composition SUMITOMO ELECTRIC INDUSTRIES (JP) 2003-11-12 EP claimed
US-20010005731-A1 Flame-retardant resin composition, and insulated wire, shielded wire and insulating tube comprising the composition SUMITOMO ELECTRIC INDUSTRIES, LTD. (JP) 2001-06-28 US claimed
EP-0848033-A1 Flame-retardant resin composition, and insulated wire, shielded wire and insulating tube comprising the composition SUMITOMO ELECTRIC INDUSTRIES, LTD. (JP) 1998-06-17 EP claimed
CN-113727854-B Thermoplastic polyurethane resin elastomer 三菱化学株式会社 2023-09-19 CN disclosed
EP-3561012-A1 DOUBLE-SIDED ADHESIVE TAPE Mitsubishi Chemical Corporation (JP) 2019-10-30 EP disclosed
US-20190300758-A1 DOUBLE-SIDED PRESSURE-SENSITIVE ADHESIVE TAPE MITSUBISHI CHEMICAL CORPORATION (JP) 2019-10-03 US disclosed
EP-0848033-B1 Flame-retardant resin composition, and insulated wire, shielded wire and insulating tube comprising the composition SUMITOMO ELECTRIC INDUSTRIES (JP) 2003-11-12 EP disclosed
US-6500508-B2 Thermoplastic resin comprising low density ethylene-alpha-olefin copolymer made using a single-site metallocene catalyst, a halogen-containing flame retardant, and zinc oxide SUMITOMO ELECTRIC FINE POLYMER, INC. (JP) 2002-12-31 US disclosed
US-20010005731-A1 Flame-retardant resin composition, and insulated wire, shielded wire and insulating tube comprising the composition SUMITOMO ELECTRIC INDUSTRIES, LTD. (JP) 2001-06-28 US disclosed
US-6204318-B1 Insulated wire comprising a flame-retardant polyolefinic resin composition SUMITOMO ELECTRIC INDUSTRIES, LTD. (JP) 2001-03-20 US disclosed
EP-0848033-A1 Flame-retardant resin composition, and insulated wire, shielded wire and insulating tube comprising the composition SUMITOMO ELECTRIC INDUSTRIES, LTD. (JP) 1998-06-17 EP disclosed