SCHEMBL7687360

SCHEMBL7687360

O=C1c2cccc(CCc3cccc4c3C(=O)N(Br)C4=O)c2C(=O)N1Br

nearest known ligand 0.50

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ANPEP P15144 1/20 0.38
DPP4 P27487 1/20 0.38
NR1H3 Q13133 3/20 0.38
NR1H2 P55055 3/20 0.38
TYMS P04818 2/20 0.35
MEN1 O00255 1/20 0.33
USP2 O75604 1/20 0.33
CASP1 P29466 1/20 0.33
BRCA1 P38398 1/20 0.33
CASP7 P55210 1/20 0.33
KMT2A Q03164 1/20 0.33
HSPA1A P0DMV8 1/20 0.33
PABPC1 P11940 1/20 0.33
CA12 O43570 1/20 0.31
CA2 P00918 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL461208 0.81 GABRA1 (0.46) ANPEPDPP4MEN1KMT2ACA12
SCHEMBL3681059 0.76 CA2 (0.44) DPP4MEN1KMT2AHSPA1APABPC1
SCHEMBL7688807 0.76
SCHEMBL1039244 0.74 DPP4 (0.50) DPP4TYMSMEN1KMT2ACA2
SCHEMBL11093043 0.74 HSPA1A (0.33) DPP4MEN1USP2CASP1BRCA1
Ethylene SCHEMBL7198617 0.73 CA2 (0.42) MEN1KMT2AHSPA1APABPC1CA12
SCHEMBL3181941 0.72 TYMS (0.30) TYMS
SCHEMBL1771 0.71 POLB (0.48) MEN1KMT2ACA12
SCHEMBL29385866 0.71 POLB (0.48) MEN1KMT2ACA12
SCHEMBL30572531 0.69 POLB (0.46) MEN1KMT2ACA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230099634-A1 STYRENE-BASED RESIN COMPOSITION, FLAME RETARDANT STYRENE-BASED RESIN COMPOSITION, MOLDED BODY, AND PATCH ANTENNA PS JAPAN CORPORATION (JP) 2023-03-30 US disclosed
US-6500889-B2 BROMINATED FLAME RETARDANT, DOLOMITE AND ONE OF: HYDROTALCITE, ZINC-SUBSTITUTED HYDROTALCITE, OR ZEOLITE; HEAT STABILIZING AJINOMOTO CO., INC. (JP) 2002-12-31 US disclosed
US-20010044488-A1 Flame-retarded thermoplastic resin composition AJINOMOTO CO. INC. (JP) 2001-11-22 US disclosed
EP-1127917-A1 Flame-retardant thermoplastic resin composition Ajinomoto Co., Inc. (JP) 2001-08-29 EP disclosed