Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 1/20 | 0.43 |
| ▸ | CASR | P41180 | 1/20 | 0.39 |
| ▸ | PTPRC | P08575 | 2/20 | 0.38 |
| ▸ | FPR3 | P25089 | 1/20 | 0.38 |
| ▸ | FPR2 | P25090 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | GRK2 | P25098 | 2/20 | 0.38 |
| ▸ | GRK3 | P35626 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | PPARA | Q07869 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | VSIR | Q9H7M9 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11093055 | 1.00 | AKR1C3 (0.43) | AKR1C3CASRPTPRCFPR3FPR2 | |
| SCHEMBL11088028 | 0.85 | AKR1C3 (0.47) | AKR1C3CASRPTPRCFPR3FPR2 | |
| SCHEMBL4490577 | 0.84 | AKR1C3 (0.60) | AKR1C3CASRCA12CA2CA9 | |
| SCHEMBL15057284 | 0.82 | HPGD (0.48) | AKR1C3MAPTMEN1LMNAKMT2A | |
| SCHEMBL11087050 | 0.81 | HDAC3 (0.52) | CA12CA1CA9MEN1LMNA | |
| SCHEMBL11087051 | 0.81 | HDAC3 (0.52) | CA12CA1CA9MEN1LMNA | |
| SCHEMBL7429994 | 0.81 | CASR (0.52) | AKR1C3CASRMAPTMEN1TP53 | |
| SCHEMBL4485291 | 0.81 | PARP14 (0.47) | AKR1C3PTPRCFPR3FPR2GRK2 | |
| SCHEMBL24077532 | 0.78 | ALDH1A1 (0.53) | PKMMAPTMEN1LMNATP53 | |
| SCHEMBL303932 | 0.77 | PKM (0.46) | PTPRCPKMMAPTCA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4464366-A | Cephem compounds having a terminal aminocarboxylic acid grouping and containing an azacyclyl(thio)ureido group | CIBA GEIGY CORPORATION (US) | 1984-08-07 | — | — | US | disclosed |