Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 3/20 | 0.46 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.46 |
| ▸ | KDR | P35968 | 5/20 | 0.44 |
| ▸ | PLK4 | O00444 | 2/20 | 0.41 |
| ▸ | NUAK1 | O60285 | 2/20 | 0.41 |
| ▸ | FLT4 | P35916 | 2/20 | 0.41 |
| ▸ | FLT3 | P36888 | 2/20 | 0.41 |
| ▸ | AURKA | O14965 | 1/20 | 0.41 |
| ▸ | CDK4 | P11802 | 1/20 | 0.41 |
| ▸ | CCND1 | P24385 | 1/20 | 0.41 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.41 |
| ▸ | SRC | P12931 | 1/20 | 0.40 |
| ▸ | TEK | Q02763 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | KIF11 | P52732 | 1/20 | 0.38 |
| ▸ | TDP2 | O95551 | 1/20 | 0.37 |
| ▸ | BACE1 | P56817 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11094421 | 0.83 | KIF11 (0.50) | PARP1PARP2KDRPLK4NUAK1 | |
| SCHEMBL11086876 | 0.80 | PTGS1 (0.44) | PARP1PARP2KDRPLK4NUAK1 | |
| SCHEMBL30587850 | 0.72 | KIF11 (0.44) | PARP1PARP2KDRKIF11TDP2 | |
| SCHEMBL16844169 | 0.72 | KIF11 (0.58) | MAPTKIF11BACE1 | |
| SCHEMBL30394422 | 0.72 | KIF11 (0.58) | MAPTKIF11BACE1 | |
| SCHEMBL11091670 | 0.69 | PTGS1 (0.57) | KDRPLK4NUAK1FLT4FLT3 | |
| SCHEMBL11083302 | 0.69 | PTGS1 (0.57) | KDRPLK4NUAK1FLT4FLT3 | |
| SCHEMBL6184759 | 0.67 | KMT2A (0.48) | KDRPLK4NUAK1FLT4FLT3 | |
| SCHEMBL11085243 | 0.66 | FABP3 (0.43) | KDRPLK4NUAK1FLT4FLT3 | |
| SCHEMBL18708246 | 0.65 | APP (0.53) | MAPTKIF11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4443616-A | Production of 3-pyrrolin-2-ones | THE PURDUE FREDERICK COMPANY (US) | 1984-04-17 | — | — | US | disclosed |