Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 5/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.44 |
| ▸ | KDR | P35968 | 2/20 | 0.39 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.39 |
| ▸ | RIPK3 | Q9Y572 | 1/20 | 0.38 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.38 |
| ▸ | TDP2 | O95551 | 1/20 | 0.38 |
| ▸ | KIF11 | P52732 | 1/20 | 0.37 |
| ▸ | PARP1 | P09874 | 2/20 | 0.36 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.36 |
| ▸ | PLK4 | O00444 | 1/20 | 0.36 |
| ▸ | AURKA | O14965 | 1/20 | 0.36 |
| ▸ | NUAK1 | O60285 | 1/20 | 0.36 |
| ▸ | CDK4 | P11802 | 1/20 | 0.36 |
| ▸ | CCND1 | P24385 | 1/20 | 0.36 |
| ▸ | FLT4 | P35916 | 1/20 | 0.36 |
| ▸ | FLT3 | P36888 | 1/20 | 0.36 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11094421 | 0.88 | KIF11 (0.50) | PTGS1PTGS2KDRKIF11PARP1 | |
| SCHEMBL11091670 | 0.83 | PTGS1 (0.57) | PTGS1PTGS2KDRGRM2PLK4 | |
| SCHEMBL11083302 | 0.83 | PTGS1 (0.57) | PTGS1PTGS2KDRGRM2PLK4 | |
| SCHEMBL11093596 | 0.80 | PARP1 (0.46) | KDRTDP2KIF11PARP1PLK4 | |
| SCHEMBL30587850 | 0.76 | KIF11 (0.44) | PTGS1PTGS2KDRTDP2KIF11 | |
| SCHEMBL12424997 | 0.71 | NPY5R (0.42) | PTGS1PTGS2NPY5RRIPK3TDP2 | |
| SCHEMBL6184759 | 0.71 | KMT2A (0.48) | PTGS1PTGS2KDRPLK4AURKA | |
| SCHEMBL5848641 | 0.71 | MAP2K4 (0.48) | PTGS1PTGS2KDM4E | |
| SCHEMBL7345190 | 0.70 | GRM2 (0.43) | PTGS1PTGS2GRM2PARP1FLT3 | |
| SCHEMBL7940597 | 0.70 | KIF11 (0.64) | NPY5RKIF11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4443616-A | Production of 3-pyrrolin-2-ones | THE PURDUE FREDERICK COMPANY (US) | 1984-04-17 | — | — | US | disclosed |