Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 4/20 | 0.44 |
| ▸ | KDR | P35968 | 1/20 | 0.44 |
| ▸ | COMT | P21964 | 1/20 | 0.41 |
| ▸ | TDP2 | O95551 | 1/20 | 0.40 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | PARP1 | P09874 | 3/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.38 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.38 |
| ▸ | AR | P10275 | 1/20 | 0.38 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.37 |
| ▸ | PIM1 | P11309 | 1/20 | 0.37 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.37 |
| ▸ | BACE1 | P56817 | 1/20 | 0.37 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11094421 | 0.76 | KIF11 (0.50) | KIF11KDRPTGS2PTGS1PARP1 | |
| SCHEMBL11086876 | 0.76 | PTGS1 (0.44) | KIF11KDRTDP2NISCHPTGS2 | |
| SCHEMBL11093596 | 0.72 | PARP1 (0.46) | KIF11KDRTDP2PARP1PARP2 | |
| SCHEMBL11096436 | 0.66 | KIF11 (0.43) | KIF11KDRCOMTTDP2NISCH | |
| SCHEMBL8352439 | 0.66 | TDP2 (0.45) | KIF11KDRCOMTTDP2NISCH | |
| SCHEMBL13290021 | 0.65 | KIF11 (0.56) | KIF11COMTARNOTUMBACE1 | |
| SCHEMBL197238 | 0.63 | KIF11 (0.78) | KIF11 | |
| SCHEMBL13410633 | 0.63 | KIF11 (0.78) | KIF11 | |
| SCHEMBL29914837 | 0.63 | KIF11 (0.78) | KIF11 | |
| SCHEMBL12675678 | 0.63 | KIF11 (1.00) | KIF11PTGS2PTGS1ESR1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4504173-A2 | 4-PHENYL-2-PYRROLIDINONES AND METHODS OF USING THEREOF | North Carolina State University (US) | 2025-02-12 | — | — | EP | disclosed |
| WO-2023196678-A2 | 4-PHENYL-2-PYRROLIDINONES AND METHODS OF USING THEREOF | NORTH CAROLINA STATE UNIVERSITY (US) | 2023-10-12 | — | — | WO | disclosed |