Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.38 |
| ▸ | PTGER2 | P43116 | 4/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.37 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.37 |
| ▸ | NAMPT | P43490 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | NPY1R | P25929 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11095919 | 0.92 | KMT2A (0.44) | KMT2APOLBPTGER2L3MBTL1ALDH1A1 | |
| SCHEMBL11090280 | 0.90 | KMT2A (0.43) | KMT2APOLBPTGER2L3MBTL1ALDH1A1 | |
| SCHEMBL11088418 | 0.90 | CYP3A4 (0.47) | KMT2AALDH1A1NAMPTCYP3A4CYP2D6 | |
| SCHEMBL11390128 | 0.89 | ALOX15 (0.47) | KMT2APOLBPTGER2ALDH1A1PTGER4 | |
| SCHEMBL11093116 | 0.89 | ALDH1A1 (0.43) | KMT2AALDH1A1NAMPTCYP3A4CYP2D6 | |
| SCHEMBL11082845 | 0.88 | KMT2A (0.41) | KMT2APOLBPTGER2L3MBTL1ALDH1A1 | |
| SCHEMBL11093019 | 0.86 | MAPT (0.48) | KMT2AL3MBTL1ALDH1A1KDM4ECYP3A4 | |
| SCHEMBL11092807 | 0.85 | LTA4H (0.47) | L3MBTL1ALDH1A1 | |
| SCHEMBL11090241 | 0.84 | KMT2A (0.44) | KMT2APOLBPTGER2L3MBTL1ALDH1A1 | |
| SCHEMBL11092108 | 0.83 | HSD17B3 (0.46) | KMT2APOLBL3MBTL1ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4486443-A | PROSTAGLANDIN-LIKE EFFECTS | BURROUGHS WELLCOME CO. (US) | 1984-12-04 | — | — | US | disclosed |
| US-4262128-A | HAVING PROSTAGLANDIN-LIKE BIOLOGICAL PROPERTIES | BURROUGHS WELLCOME CO. (US) | 1981-04-14 | — | — | US | disclosed |