Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR1 | Q9BXC0 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.33 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.32 |
| ▸ | CES1 | P23141 | 2/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8517309 | 0.67 | ALDH1A1 (0.41) | ALDH1A1NPSR1MAPTKDM4ESMN1; SMN2 | |
| SCHEMBL5178841 | 0.64 | MGLL (0.55) | HCAR1ALDH1A1NPSR1NOTUMMAPT | |
| SCHEMBL10948802 | 0.64 | MEN1 (0.49) | ALDH1A1MAPTSMN1; SMN2MEN1KMT2A | |
| SCHEMBL11151988 | 0.64 | KMT2A (0.50) | HCAR1ALDH1A1MAPTKDM4ESMN1; SMN2 | |
| SCHEMBL11466957 | 0.62 | FAAH (0.33) | KDM2BKDM4C | |
| SCHEMBL30438638 | 0.62 | KDM2B (0.33) | KDM2BKDM4C | |
| SCHEMBL348089 | 0.61 | CYP3A4 (0.62) | ALDH1A1NOTUMCYP3A4MAPK1 | |
| SCHEMBL29368277 | 0.61 | CYP3A4 (0.62) | ALDH1A1NOTUMCYP3A4MAPK1 | |
| Methane SCHEMBL23466796 | 0.58 | CYP3A4 (0.59) | ALDH1A1NOTUMCYP3A4MAPK1 | |
| SCHEMBL904518 | 0.58 | DRD2 (0.42) | HCAR1ALDH1A1NPSR1NOTUMCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0284030-B1 | PYRAZOLE DERIVATIVE, PROCESS THEREOF AND HERBICIDE CONTAINING THE DERIVATIVE AS AN EFFECTIVE COMPONENT | Otsuka Kagaku Kabushiki Kaisha (JP) | 1993-03-17 | — | — | EP | disclosed |
| EP-0284030-A1 | Pyrazole derivative, process thereof and herbicide containing the derivative as an effective component | Otsuka Kagaku Kabushiki Kaisha (JP) | 1988-09-28 | — | — | EP | disclosed |