Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 1/20 | 0.69 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.51 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.45 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.44 |
| ▸ | MRGPRX4 | Q96LA9 | 3/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | HPD | P32754 | 1/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.43 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.43 |
| ▸ | TTR | P02766 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11095924 | 0.88 | CXCL8 (0.68) | CHRM1CXCL8CAMK2ASLC6A2SLC6A4 | |
| SCHEMBL11093624 | 0.85 | CHRM1 (0.50) | CHRM1PLA2G1BMAPTATG4BMRGPRX4 | |
| SCHEMBL11090351 | 0.84 | CXCL8 (0.55) | CHRM1CXCL8CAMK2ATTR | |
| SCHEMBL11089397 | 0.84 | CHRM1 (0.46) | CHRM1CXCL8CAMK2AMAPTSLC6A2 | |
| SCHEMBL10585649 | 0.83 | ALDH1A1 (0.53) | CHRM1PLA2G1BMAPTATG4BMRGPRX4 | |
| Fenclofenac SCHEMBL25161 | 0.82 | CHRM1 (1.00) | CHRM1CXCL8CAMK2APLA2G1BMAPT | |
| Fenclofenac SCHEMBL30509659 | 0.82 | CHRM1 (1.00) | CHRM1CXCL8CAMK2APLA2G1BMAPT | |
| Fenclofenac SCHEMBL29438086 | 0.82 | CHRM1 (1.00) | CHRM1CXCL8CAMK2APLA2G1BMAPT | |
| Fenclofenac SCHEMBL28279765 | 0.82 | CHRM1 (1.00) | CHRM1CXCL8CAMK2APLA2G1BMAPT | |
| Fenclofenac SCHEMBL9692633 | 0.81 | CHRM1 (0.97) | CHRM1CXCL8CAMK2APLA2G1BMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4472433-A | Phenoxyphenyl acetic acids and their medicinal use | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1984-09-18 | — | — | US | disclosed |
| EP-0008226-B1 | PHENYL-ALKANOIC ACID DERIVATIVES, THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1983-11-02 | — | — | EP | disclosed |
| EP-0008226-A2 | Phenyl-alkanoic acid derivatives, the preparation thereof and pharmaceutical compositions containing them | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1980-02-20 | — | — | EP | disclosed |