Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | DAO | P14920 | 1/20 | 0.32 |
| ▸ | TGM2 | P21980 | 1/20 | 0.31 |
| ▸ | CES2 | O00748 | 1/20 | 0.31 |
| ▸ | CES1 | P23141 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17537375 | 0.73 | DAO (0.35) | DAOTGM2CES2CES1 | |
| SCHEMBL18928130 | 0.68 | GRM4 (0.30) | DAO | |
| SCHEMBL11716549 | 0.67 | GRM7 (0.34) | — | |
| SCHEMBL12660986 | 0.65 | DAO (0.33) | DAOTGM2CES2CES1 | |
| SCHEMBL11086038 | 0.64 | DAO (0.40) | GAADAOTGM2CES2CES1 | |
| SCHEMBL14268820 | 0.63 | TERT (0.38) | — | |
| SCHEMBL17543544 | 0.61 | ALDH1A1 (0.42) | DAO | |
| SCHEMBL20356023 | 0.59 | GPR84 (0.41) | TGM2CES2CES1 | |
| SCHEMBL28165601 | 0.59 | CES2 (0.30) | CES2CES1 | |
| SCHEMBL289690 | 0.59 | CES2 (0.44) | GAACES2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4481356-A | MEDICAL DIAGNOSIS | THE UPJOHN COMPANY (US) | 1984-11-06 | — | — | US | disclosed |
| US-4366320-A | 4-Substituted phenyl-1,2,4-triazoline-3,5-diones and their dihydro analogs as analytical reagents | THE UPJOHN COMPANY (US) | 1982-12-28 | — | — | US | disclosed |