Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 8/20 | 0.44 |
| ▸ | CES1 | P23141 | 8/20 | 0.44 |
| ▸ | ERN1 | O75460 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 3/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | CA4 | P22748 | 2/20 | 0.36 |
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | SPR | P35270 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17056077 | 0.84 | GAA (0.39) | CES2CES1ERN1GAAKMT2A | |
| SCHEMBL2397770 | 0.82 | ALDH1A1 (0.41) | CES2CES1GAAKMT2AALDH1A1 | |
| SCHEMBL1085223 | 0.80 | DGAT1 (0.41) | CES2CES1GAAKMT2AALDH1A1 | |
| SCHEMBL9712503 | 0.80 | HDAC1 (0.38) | GAAKMT2AALDH1A1ALOX15CA1 | |
| SCHEMBL23764727 | 0.78 | LMNA (0.44) | CES2CES1ALDH1A1ALOX15CA1 | |
| Hydrochloric Acid SCHEMBL11874647 | 0.78 | ALDH1A1 (0.35) | CES2CES1ALDH1A1ALOX15CA1 | |
| SCHEMBL10029664 | 0.78 | CES2 (0.48) | CES2CES1ERN1GAAKMT2A | |
| SCHEMBL4514781 | 0.77 | ALDH1A1 (0.52) | CES2CES1ERN1KMT2AALDH1A1 | |
| SCHEMBL16408244 | 0.77 | CES2 (0.45) | CES2CES1GAAALDH1A1ALOX15 | |
| SCHEMBL1026644 | 0.77 | CES2 (0.39) | CES2CES1ERN1GAAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 412 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-120044163-A | HPLC analysis and detection method for 2,4, 6-trifluoro benzoyl chloride and related substances thereof | 复星万邦(江苏)医药集团有限公司 | 2025-05-27 | — | — | CN | claimed |
| CN-114144408-B | Large scale preparation of 2,4, 6-trifluoro-N- [6- (1-methyl-piperidine-4-carbonyl) -pyridin-2-yl ] -benzamide hemisuccinate and process and intermediates for preparing 2,4, 6-trifluoro-N- [6- (1-methyl-piperidine-4-carbonyl) -pyridin-2-yl ] -benzamide acetate | 伊莱利利公司 | 2025-04-15 | — | — | CN | claimed |
| CN-118047752-A | Lamiditan hemisuccinate impurity and preparation method thereof | 江苏万邦生化医药集团有限责任公司 | 2024-05-17 | — | — | CN | claimed |
| CN-113045540-B | Preparation method of masmipide | 上海天慈国际药业有限公司 | 2024-02-13 | — | — | CN | claimed |
| CN-114751900-B | D-A type organic luminescent material and preparation method and application thereof | 南京邮电大学 | 2023-09-12 | — | — | CN | claimed |
| CN-115557932-A | Preparation method of lamidottan dimer impurity | 江苏万邦生化医药集团有限责任公司 | 2023-01-03 | — | — | CN | claimed |
| CN-114751900-A | D-A type organic luminescent material and preparation method and application thereof | 南京邮电大学 | 2022-07-15 | — | — | CN | claimed |
| CN-114144408-A | Process and intermediates for large scale preparation of 2,4, 6-trifluoro-N- [6- (1-methyl-piperidine-4-carbonyl) -pyridin-2-yl ] -benzamide hemisuccinate and preparation of 2,4, 6-trifluoro-N- [6- (1-methyl-piperidine-4-carbonyl) -pyridin-2-yl ] -benzamide acetate | 伊莱利利公司 | 2022-03-04 | — | — | CN | claimed |
| CN-113045540-A | Preparation method of rasemiptan | 上海天慈国际药业有限公司 | 2021-06-29 | — | — | CN | claimed |
| CN-110386918-B | Preparation method of 5-HT1F agonist compound | 新发药业有限公司 | 2020-06-09 | — | — | CN | claimed |
| CN-110386918-A | A kind of preparation method of 5-HT1F agonist compound | 新发药业有限公司 | 2019-10-29 | — | — | CN | claimed |
| CN-103487455-B | A kind of method of hydroxy-containing compounds in Quantitative detection olive oil | SHANGHAI UNIVERSITY (CN) | 2016-04-27 | — | — | CN | claimed |
| US-8697876-B2 | Compositions and methods of synthesis of pyridinolypiperidine 5-HT1F agonists | COLUCID PHARMACEUTICALS, INC. (US) | 2014-04-15 | — | — | US | claimed |
| CN-103487455-A | Novel method for quick quantitative determination of hydroxy components in olive oil | UNIV SHANGHAI | 2014-01-01 | — | — | CN | claimed |
| US-20130072524-A1 | Compositions And Methods Of Synthesis Of Pyridinolypiperidine 5-HT1F Agonists | APTUIT (EDINBURGH) LTD. (GB) | 2013-03-21 | — | — | US | claimed |
| WO-2011123654-A1 | COMPOSITIONS AND METHODS OF SYNTHESIS OF PYRIDINOYLPIPERIDINE 5-HT1F AGONISTS | COLUCID PHARMACEUTICALS, INC. (US) | 2011-10-06 | — | — | WO | claimed |
| EP-0440329-A1 | S-substituted carbonyl substituted betathioacrylamide biocides and fungicides | ROHM AND HAAS COMPANY (US) | 1991-08-07 | — | — | EP | claimed |
| CN-114573555-B | Preparation method of compound for treating migraine | 上海天慈国际药业有限公司 | 2026-02-17 | — | — | CN | disclosed |
| EP-0060617-A1 | Fluorobenzyl cyclopropane carboxylates, their preparation, compositions and use as insecticides | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1982-09-22 | — | — | EP | disclosed |
| EP-0031199-A1 | Substituted benzyl esters of cyclopropane carboxylic acids and their preparation, compositions containing them and methods of combating insect pests therewith, and substituted benzyl alcohols | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1981-07-01 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130072524-A1 | Compositions And Methods Of Synthesis Of Pyridinolypiperidine 5-HT1F Agonists | HTR1F, HTR1A, HTR1D | CES2 4069/4885CES1 2314/4885ERN1 4550/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.