Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11098803 | 0.86 | IDO1 (0.43) | TP53GAAALDH1A1KMT2AL3MBTL1 | |
| SCHEMBL11160756 | 0.84 | ALDH1A1 (0.51) | TP53GAAALDH1A1KMT2AMEN1 | |
| SCHEMBL11097622 | 0.80 | ALDH1A1 (0.56) | TP53GAAALDH1A1KMT2AMEN1 | |
| SCHEMBL5174047 | 0.78 | VDR (0.41) | TP53GAAALDH1A1KMT2AL3MBTL1 | |
| SCHEMBL6202033 | 0.78 | ALDH1A1 (0.50) | TP53GAAALDH1A1MAPTLMNA | |
| SCHEMBL11098540 | 0.78 | TP53 (0.53) | TP53GAAALDH1A1KMT2AL3MBTL1 | |
| SCHEMBL11269744 | 0.76 | TP53 (0.44) | TP53GAAALDH1A1KMT2AMEN1 | |
| SCHEMBL7609717 | 0.74 | AGTR1 (0.38) | — | |
| SCHEMBL11162148 | 0.74 | LMNA (0.49) | GAAALDH1A1KMT2AL3MBTL1MEN1 | |
| SCHEMBL11163273 | 0.72 | ALDH1A1 (0.59) | TP53GAAALDH1A1KMT2AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0028834-B1 | IMIDAZOLE-5-ACETIC ACID DERIVATIVES, THEIR PRODUCTION AND USE | Takeda Chemical Industries, Ltd. (JP) | 1984-01-18 | — | — | EP | disclosed |
| US-4355040-A | Hypotensive imidazole-5-acetic acid derivatives | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1982-10-19 | — | — | US | disclosed |