Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR35 | Q9HC97 | 3/20 | 0.62 |
| ▸ | TSHR | P16473 | 4/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 3/20 | 0.42 |
| ▸ | CA1 | P00915 | 3/20 | 0.42 |
| ▸ | CA2 | P00918 | 3/20 | 0.42 |
| ▸ | CA9 | Q16790 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.41 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.41 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.41 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.41 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2232801 | 0.86 | GPR35 (0.61) | GPR35TSHRALOX15MAPK1L3MBTL1 | |
| SCHEMBL4847900 | 0.80 | GPR35 (0.80) | GPR35TSHRALOX15MAPK1HSD17B10 | |
| SCHEMBL11113072 | 0.80 | GPR35 (0.67) | GPR35TSHRALOX15MAPK1HSD17B10 | |
| SCHEMBL7786697 | 0.80 | TSHR (0.60) | GPR35TSHRALOX15MAPK1L3MBTL1 | |
| SCHEMBL349045 | 0.80 | GPR35 (0.55) | GPR35TSHRMAPK1HSD17B10L3MBTL1 | |
| SCHEMBL29816776 | 0.80 | GPR35 (0.55) | GPR35TSHRMAPK1HSD17B10L3MBTL1 | |
| SCHEMBL2970574 | 0.78 | ALDH1A1 (0.63) | GPR35TSHRMAPK1L3MBTL1CYP3A4 | |
| SCHEMBL8449685 | 0.78 | ALDH1A1 (0.66) | GPR35TSHRALOX15MAPK1HSD17B10 | |
| SCHEMBL4264263 | 0.78 | ERN1 (0.51) | GPR35TSHRALOX15MAPK1HSD17B10 | |
| SCHEMBL322531 | 0.77 | GPR35 (1.00) | GPR35TSHRALOX15MAPK1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3684767-B1 | HETEROCYCLIC COMPOUNDS AS PAD INHIBITORS | Jubilant Epipad LLC (US) | 2024-04-24 | — | — | EP | disclosed |
| US-4473374-A | Nitrated coupler compounds useful in direct dyeing and simultaneous oxidation and direct dyeing of keratinic fibers | SOCIETE ANONYME DITE: L'OREAL (FR) | 1984-09-25 | — | — | US | disclosed |
| US-4367235-A | CARDIOVASCULAR DISORDERS | BOEHRINGER MANNHEIM GMBH (DE) | 1983-01-04 | — | — | US | disclosed |
| US-4330291-A | Nitrated coupler compounds useful in direct dyeing and simultaneous oxidation and direct dyeing of keratinic fibers | SOCIETE ANONYME DITE: L'OREAL (FR) | 1982-05-18 | — | — | US | disclosed |
| EP-0003298-B1 | 4-HYDROXY-2-BENZIMIDAZOLIN-THION DERIVATIVES, PROCESS FOR THEIR PREPARATION AND MEDICAMENTS CONTAINING THEM | Roche Diagnostics GmbH (DE) | 1981-03-25 | — | — | EP | disclosed |
| US-4215134-A | B-RECEPTOR BLOCKING AGENTS | BOEHRINGER MANNHEIM GMBH (DE) | 1980-07-29 | — | — | US | disclosed |
| EP-0003298-A2 | 4-Hydroxy-2-benzimidazolin-thion derivatives, process for their preparation and medicaments containing them | Roche Diagnostics GmbH (DE) | 1979-08-08 | — | — | EP | disclosed |
| EP-0000784-A1 | 4-Hydroxy-2-benzimidazolinone derivatives, process for their preparation and their use in medicaments | Roche Diagnostics GmbH (DE) | 1979-02-21 | — | — | EP | disclosed |