Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.63 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.63 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 4/20 | 0.53 |
| ▸ | CTSB | P07858 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.42 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.42 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.42 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.42 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.42 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.42 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | G6PD | P11413 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2232801 | 0.87 | GPR35 (0.61) | ALDH1A1CYP3A4GPR35TSHRCTSB | |
| SCHEMBL27561588 | 0.82 | GPR35 (0.55) | ALDH1A1CYP3A4GPR35TSHRCYP1A2 | |
| SCHEMBL22968279 | 0.82 | GPR35 (0.55) | ALDH1A1CYP3A4GPR35TSHRCYP1A2 | |
| SCHEMBL7786697 | 0.82 | TSHR (0.60) | ALDH1A1CYP3A4GPR35TSHRCYP1A2 | |
| SCHEMBL349045 | 0.82 | GPR35 (0.55) | ALDH1A1CYP3A4GPR35TSHRCYP1A2 | |
| SCHEMBL29816776 | 0.82 | GPR35 (0.55) | ALDH1A1CYP3A4GPR35TSHRCYP1A2 | |
| SCHEMBL2783704 | 0.79 | ALDH1A1 (0.68) | ALDH1A1CYP3A4TSHRCTSBKDM4E | |
| SCHEMBL29706644 | 0.79 | ALDH1A1 (0.68) | ALDH1A1CYP3A4TSHRCTSBKDM4E | |
| SCHEMBL11539985 | 0.79 | GPR35 (0.68) | ALDH1A1CYP3A4GPR35TSHRCYP1A2 | |
| SCHEMBL22232253 | 0.78 | GPR35 (0.52) | ALDH1A1CYP3A4GPR35TSHRCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 99 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025171194-A9 | CRYSTALLINE FORMS OF (R)-6-CHLORO-3-((1-(2-CYANO-7-METHYL-3-MORPHOLINOQUINOXALIN-5-YL)ETHYL)AMINO)PICOLINIC ACID | Mirati Therapeutics, Inc. (US) | 2026-05-21 | — | — | WO | disclosed |
| EP-4709714-A1 | SUBSTITUTED QUINOXALINES | Mirati Therapeutics, Inc. (US) | 2026-03-18 | — | — | EP | disclosed |
| CN-121586713-A | Quinoline derivatives and pharmaceutical compositions thereof for the treatment of diseases | 百济神州(苏州)生物科技有限公司 | 2026-02-27 | — | — | CN | disclosed |
| US-12545639-B2 | 3-substituted phenylamidine compounds, preparation and use thereof | PI INDUSTRIES LTD. (IN) | 2026-02-10 | — | — | US | disclosed |
| US-12528827-B2 | Tricyclic heteroaryl-substituted quinoline and azaquinoline compounds as PAR4 inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 2026-01-20 | — | — | US | disclosed |
| EP-4647426-A2 | 3-SUBSTITUTED PHENYLAMIDINE COMPOUNDS, PREPARATION AND USE THEREOF | PI Industries Ltd. (IN) | 2025-11-12 | — | — | EP | disclosed |
| US-20250276960-A1 | CRYSTALLINE FORMS OF (R)-6-CHLORO-3-((1-(2-CYANO-7-METHYL-3-MORPHOLINOQUINOXALIN-5-YL)ETHYL)AMINO)PICOLINIC ACID | Mirati Therapeutics, Inc. (US) | 2025-09-04 | — | — | US | disclosed |
| EP-4596551-A1 | COMPOUNDS WITH ANTI-KRAS MUTANT TUMOR ACTIVITY | Trasveda Ltd. (KY) | 2025-08-06 | — | — | EP | disclosed |
| US-20250121073-A1 | IRAK DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS, INC. | 2025-04-17 | — | — | US | disclosed |
| WO-2025021217-A1 | QUINOLINE DERIVATIVES AND PHARMARCEUTICAL COMPOSITIONS THEREOF FOR THE TREATMENT OF DISEASE | BEIGENE SWITZERLAND GMBH (CH) | 2025-01-30 | — | — | WO | disclosed |
| EP-0559843-B1 | SUBSTITUTED N-HETEROBICYCLIC HERBICIDES | DU PONT (US) | 1994-09-14 | — | — | EP | disclosed |
| EP-0559843-A1 | SUBSTITUTED N-HETEROBICYCLIC HERBICIDES. | DU PONT (US) | 1993-09-15 | — | — | EP | disclosed |
| WO-1992009578-A1 | SUBSTITUTED FUSED HETEROCYCLIC HERBICIDES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1992-06-11 | — | — | WO | disclosed |
| US-5110347-A | Pre- and postemergence; quinoxaline derivatives | E. I DU PONT DE NEMOURS AND COMPANY (US) | 1992-05-05 | — | — | US | disclosed |
| US-4479899-A | OF POLYESTERS | BAYER AKTIENGESELLSCHAFT (DE) | 1984-10-30 | — | — | US | disclosed |
| US-4452609-A | Dyeing red with 2,6-dicyano-2'-sulfonamido-4'-amino-azo-benzenes | BAYER AKTIENGESELLSCHAFT (DE) | 1984-06-05 | — | — | US | disclosed |
| US-4237048-A | COLORFASTNESS; FOR DYEING NATURAL AND SYNTHETIC FIBERS | BAYER AKTIENGESELLSCHAFT (DE) | 1980-12-02 | — | — | US | disclosed |
| US-4105655-A | PHENYL-AZO-ANILINO DYESTUFF | BAYER AKTIENGESELLSCHAFT (DE) | 1978-08-08 | — | — | US | disclosed |
| US-4083844-A | Phenylazo orthocyano phenylazo or orthocyano phenylazo phenylazo containing dyestuffs | BAYER AKTIENGESELLSCHAFT (DT) | 1978-04-11 | — | — | US | disclosed |
| US-3962209-A | PROCESS FOR PREPARING AZO DYESTUFFS WITH ORTHO-AZO CYANO GROUPS BY CYANO EXCHANGE OF METAL CYANIDES AND HALO DYESTUFFS | BAYER AKTIENGESELLSCHAFT (DT) | 1976-06-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250276960-A1 | CRYSTALLINE FORMS OF (R)-6-CHLORO-3-((1-(2-CYANO-7-METHYL-3-MORPHOLINOQUINOXALIN-5-YL)ETHYL)AMINO)PICOLINIC ACID | UACA, CA6, CALU | ALDH1A1 3833/4885CYP3A4 2869/4885GPR35 3858/4885 |
| US-20250121073-A1 | IRAK DEGRADERS AND USES THEREOF | IRAK2, IRAK3, IRAK1 | ALDH1A1 2776/4885CYP3A4 2542/4885GPR35 3025/4885 |
| US-12545639-B2 | 3-substituted phenylamidine compounds, preparation and use thereof | CBR1, CBR3, HCCS | ALDH1A1 2035/4885CYP3A4 264/4885GPR35 3991/4885 |
| US-12528827-B2 | Tricyclic heteroaryl-substituted quinoline and azaquinoline compounds as PAR4 inhibitors | F2RL3, F2R, PF4 | ALDH1A1 1173/4885CYP3A4 23/4885GPR35 2279/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.