SCHEMBL11096853

SCHEMBL11096853

CCC1CCC(C2(c3ccc(C)cc3)CCCCC2)CC1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC6A4 P31645 7/20 0.37
SLC6A2 P23975 6/20 0.37
SLC6A3 Q01959 6/20 0.37
KCNH2 Q12809 3/20 0.37
SSTR3 P32745 1/20 0.34
OPRM1 P35372 3/20 0.33
OPRD1 P41143 2/20 0.33
OPRK1 P41145 2/20 0.33
OPRL1 P41146 2/20 0.33
CYP2D6 P10635 2/20 0.33
CYP1A1 P04798 1/20 0.33
CYP1A2 P05177 1/20 0.33
CYP2C19 P33261 1/20 0.33
HSD11B1 P28845 2/20 0.33
HSD11B2 P80365 2/20 0.33
NPC1 O15118 1/20 0.33
RAB9A P51151 1/20 0.33
KMT2A Q03164 1/20 0.32
ESR1 P03372 1/20 0.32
ESR2 Q92731 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7760357 0.80 SLC6A3 (0.53) SLC6A4SLC6A2SLC6A3KCNH2OPRM1
SCHEMBL10778228 0.78 SLC6A4 (0.44) SLC6A4SLC6A2SLC6A3KCNH2CYP2D6
SCHEMBL9225672 0.77 SLC6A4 (0.36) SLC6A4SLC6A2SLC6A3OPRM1OPRD1
SCHEMBL19801264 0.77 SLC6A4 (0.36) SLC6A4SLC6A2SLC6A3KCNH2OPRM1
SCHEMBL8921684 0.76 SLC6A3 (0.50) SLC6A4SLC6A2SLC6A3KCNH2OPRM1
Formic Acid SCHEMBL8169084 0.75 SLC6A2 (0.40) SLC6A4SLC6A2SLC6A3KCNH2CYP2D6
SCHEMBL9177828 0.75 SLC6A3 (0.42) SLC6A4SLC6A2SLC6A3KCNH2OPRM1
SCHEMBL8435345 0.75 OPRM1 (0.41) SLC6A4SLC6A2SLC6A3KCNH2OPRM1
SCHEMBL9177824 0.75 SLC6A3 (0.42) SLC6A4SLC6A2SLC6A3KCNH2OPRM1
SCHEMBL8172658 0.75 SLC6A2 (0.33) SLC6A4SLC6A2SLC6A3KCNH2OPRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4477369-A New high temperature liquid-crystalline substances consisting of 4 or 5 six-member-rings and liquid-crystalline compositions containing same CHISSO CORPORATION (JP) 1984-10-16 US disclosed