Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.57 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MMP1 | P03956 | 1/20 | 0.40 |
| ▸ | MMP2 | P08253 | 1/20 | 0.40 |
| ▸ | MMP3 | P08254 | 1/20 | 0.40 |
| ▸ | MMP9 | P14780 | 1/20 | 0.40 |
| ▸ | MMP14 | P50281 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL362441 | 0.82 | LMNA (0.62) | ATMSLC6A3LMNAPOLBHPGD | |
| SCHEMBL9538880 | 0.81 | ATM (0.81) | ATMSLC6A3LMNAPOLBMAPT | |
| SCHEMBL6336570 | 0.79 | ATM (0.58) | ATMSLC6A3LMNASMN1; SMN2 | |
| SCHEMBL8257597 | 0.79 | ATM (0.58) | ATMSLC6A3LMNASMN1; SMN2 | |
| SCHEMBL2049574 | 0.79 | HPGD (0.59) | ATMSLC6A3LMNAPOLBHPGD | |
| SCHEMBL27385604 | 0.79 | ALDH1A1 (0.46) | LMNAPOLBMAPTHPGDKMT2A | |
| SCHEMBL7390419 | 0.78 | GABBR2 (0.53) | LMNAMAPT | |
| SCHEMBL13544537 | 0.78 | SMN1; SMN2 (0.62) | ATMSLC6A3LMNAPOLBMAPT | |
| SCHEMBL6690257 | 0.78 | ATM (0.57) | ATMSLC6A3LMNAPOLBKCNA5 | |
| SCHEMBL22950648 | 0.78 | ATM (0.57) | ATMSLC6A3LMNAPOLBKCNA5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0067080-B1 | N-FLUORINATED BENZYL AMIDES AND PROCESS FOR THEIR PREPARATION | RHONE-POULENC SPECIALITES CHIMIQUES (FR) | 1984-11-21 | — | — | EP | disclosed |
| EP-0067080-A1 | N-fluorinated benzyl amides and process for their preparation | RHONE-POULENC SPECIALITES CHIMIQUES (FR) | 1982-12-15 | — | — | EP | disclosed |