Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A2 | P31213 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | HTT | P42858 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | EYA2 | O00167 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | CES2 | O00748 | 1/20 | 0.47 |
| ▸ | CES1 | P23141 | 1/20 | 0.47 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.46 |
| ▸ | PYGL | P06737 | 1/20 | 0.45 |
| ▸ | HPSE | Q9Y251 | 1/20 | 0.45 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.44 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11093863 | 0.87 | KDM4E (0.50) | LMNAHTTSMN1; SMN2MAPTEYA2 | |
| SCHEMBL6052442 | 0.87 | VCAM1 (0.53) | LMNAHTTSMN1; SMN2MAPTEYA2 | |
| SCHEMBL11092310 | 0.85 | MAPK1 (0.51) | LMNAHTTSMN1; SMN2MAPTEYA2 | |
| SCHEMBL5149578 | 0.81 | MEN1 (0.55) | LMNAHTTSMN1; SMN2MAPTEYA2 | |
| SCHEMBL11095993 | 0.80 | VCAM1 (0.50) | LMNAHTTSMN1; SMN2MAPTEYA2 | |
| SCHEMBL11087491 | 0.80 | VCAM1 (0.57) | LMNAHTTSMN1; SMN2MAPTEYA2 | |
| SCHEMBL5172391 | 0.80 | ALDH1A1 (0.66) | LMNAHTTSMN1; SMN2MAPTEYA2 | |
| SCHEMBL11087204 | 0.80 | HSPB1 (0.66) | LMNAHTTSMN1; SMN2MAPTEYA2 | |
| SCHEMBL8156678 | 0.78 | CES2 (0.56) | LMNAHTTSMN1; SMN2MAPTKDM4E | |
| SCHEMBL23417642 | 0.78 | POLB (0.57) | SRD5A2POLBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4254144-A | Substituted benzonitriles having antiviral activity | THE DOW CHEMICAL COMPANY (US) | 1981-03-03 | — | — | US | claimed |
| EP-0034263-B1 | SUBSTITUTED BENZONITRILES AND COMPOSITIONS FOR INHIBITING VIRUSES | THE DOW CHEMICAL COMPANY (US) | 1984-09-26 | — | — | EP | disclosed |
| US-4332820-A | ESPECIALLY EFFECTIVE AGAINST PICORNOVIRUSES | THE DOW CHEMICAL COMPANY (US) | 1982-06-01 | — | — | US | disclosed |
| EP-0034263-A2 | Substituted benzonitriles and compositions for inhibiting viruses | THE DOW CHEMICAL COMPANY (US) | 1981-08-26 | — | — | EP | disclosed |
| US-4254144-A | Substituted benzonitriles having antiviral activity | THE DOW CHEMICAL COMPANY (US) | 1981-03-03 | — | — | US | disclosed |