Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 3/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | KIF11 | P52732 | 1/20 | 0.36 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.35 |
| ▸ | PTGFR | P43088 | 3/20 | 0.34 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11093241 | 0.87 | PTGFR (0.34) | FFAR1HTR2AHTR2CADRA1AOPRK1 | |
| SCHEMBL11096016 | 0.83 | AKR1B1 (0.41) | FFAR1ADRA1AAKR1B1ALDH1A1TSHR | |
| SCHEMBL11093234 | 0.82 | ALDH1A1 (0.39) | ALDH1A1TSHRHTTKMT2A | |
| SCHEMBL21632134 | 0.82 | HTR2A (0.38) | FFAR1HTR2AHTR2CADRA1AOPRK1 | |
| SCHEMBL11092174 | 0.82 | TDP1 (0.40) | FFAR1ALDH1A1TSHR | |
| SCHEMBL11093239 | 0.82 | ALDH1A1 (0.34) | ALDH1A1PTGFRHTTKMT2A | |
| SCHEMBL8359862 | 0.81 | KCNN4 (0.41) | FFAR1ALDH1A1CYP1A2CYP2D6TSHR | |
| SCHEMBL11103356 | 0.81 | L3MBTL1 (0.39) | FFAR1ALDH1A1CYP1A2CYP2D6TSHR | |
| SCHEMBL11089297 | 0.80 | FFAR1 (0.39) | FFAR1AKR1B1ALDH1A1CYP1A2CYP2D6 | |
| SCHEMBL7128706 | 0.79 | L3MBTL1 (0.43) | FFAR1HTR2AHTR2CADRA1AOPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4460604-A | ANALGESICS, NARCOTIC ANTAGONIST | THE UPJOHN COMPANY (US) | 1984-07-17 | — | — | US | disclosed |
| US-4180584-A | ANALGESIC; NARCOTIC ANTAGONIST | THE UPJOHN COMPANY (US) | 1979-12-25 | — | — | US | disclosed |
| US-4065573-A | ANALGESICS | THE UPJOHN COMPANY (US) | 1977-12-27 | — | — | US | disclosed |