Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA1 | P42261 | 1/20 | 0.52 |
| ▸ | PTPN1 | P18031 | 4/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | CTSS | P25774 | 1/20 | 0.46 |
| ▸ | CTSK | P43235 | 1/20 | 0.46 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.45 |
| ▸ | SRC | P12931 | 1/20 | 0.43 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11207112 | 0.83 | GRIA1 (0.59) | GRIA1PTPN1CTSSCTSKSRC | |
| SCHEMBL10608759 | 0.82 | CTSS (0.67) | GRIA1PTPN1CTSSCTSKSRC | |
| SCHEMBL11209492 | 0.81 | LMNA (0.48) | PTPN1LMNASMN1; SMN2CTSSCTSK | |
| SCHEMBL8406437 | 0.79 | CA2 (0.60) | PTPN1LMNASMN1; SMN2MEN1KMT2A | |
| SCHEMBL11208510 | 0.79 | CA2 (0.60) | PTPN1LMNASMN1; SMN2MEN1KMT2A | |
| SCHEMBL10604163 | 0.79 | CA2 (0.60) | PTPN1LMNASMN1; SMN2MEN1KMT2A | |
| SCHEMBL7065015 | 0.77 | MGLL (0.48) | GRIA1PTPN1ALDH1A1 | |
| SCHEMBL16316818 | 0.77 | MEN1 (0.48) | LMNAALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL6139152 | 0.77 | MEN1 (0.48) | LMNAALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL11205081 | 0.77 | MEN1 (0.48) | LMNAALDH1A1SMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0094844-A2 | Drug-carrier conjugates | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1983-11-23 | — | — | EP | disclosed |