Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA1 | P42261 | 4/20 | 0.59 |
| ▸ | CTSS | P25774 | 1/20 | 0.50 |
| ▸ | CTSK | P43235 | 1/20 | 0.50 |
| ▸ | CHRND | Q07001 | 5/20 | 0.46 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.46 |
| ▸ | CHRNG | P07510 | 1/20 | 0.46 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.46 |
| ▸ | SRC | P12931 | 1/20 | 0.46 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.45 |
| ▸ | PTPRA | P18433 | 1/20 | 0.45 |
| ▸ | GNPAT | O15228 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10608759 | 0.86 | CTSS (0.67) | GRIA1CTSSCTSKSRCPTPN1 | |
| SCHEMBL11209498 | 0.83 | GRIA1 (0.52) | GRIA1CTSSCTSKSRCAVPR1A | |
| SCHEMBL11207110 | 0.79 | CTSS (0.44) | GRIA1CTSSCTSKSRCGNPAT | |
| SCHEMBL10892650 | 0.79 | GRIA1 (0.48) | GRIA1CTSSCTSKCHRNDCHRNA1 | |
| SCHEMBL11097657 | 0.79 | GRIA1 (0.48) | GRIA1CTSSCTSKCHRNDCHRNA1 | |
| SCHEMBL23933904 | 0.77 | GRIA1 (0.70) | GRIA1CTSSCTSKCHRNDCHRNA1 | |
| SCHEMBL23933905 | 0.77 | GRIA1 (0.70) | GRIA1CTSSCTSKCHRNDCHRNA1 | |
| SCHEMBL8407536 | 0.77 | LMNA (0.59) | CTSSCTSKGNPAT | |
| SCHEMBL28820766 | 0.77 | LMNA (0.59) | CTSSCTSKGNPAT | |
| SCHEMBL23933822 | 0.76 | GRIA1 (0.69) | GRIA1CTSSCTSKCHRNDCHRNA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0094844-A2 | Drug-carrier conjugates | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1983-11-23 | — | — | EP | disclosed |